宫颈癌新辅助化疗的疗效分析

目的:探讨新辅助化疗对Ib2～IIb期宫颈癌的疗效。方法:选择2008年1月～2012年4月经病理确诊的36例Ib2～IIb期宫颈癌患者给予紫杉醇加卡铂1～3个疗程化疗,评估疗效显著者行手术治疗。结果:化疗后肿瘤直径多数均有不同程度的缩小,有效率达75%,大多数患者能手术治疗切除病灶,仅少数患者无法行手术治疗。结论:术前新辅助化疗对宫颈癌Ib2～IIb期治疗安全有效,缩小肿瘤体积,提高手术切除率及疗效,为无法手术的患者创造手术可能,为治疗该病的有效治疗手段。

Analysis on curative efficacy of neoadjuvant chemotherapy for cervical cancer

Objective:To explore the curative effect of neoadjuvant chemotherapy for cervical cancer of stage Ib2-IIb.Methods:Thirty-six patients with cervical cancer of stage Ib2-IIb who were diagnosed definitely in the hospital by pathological examination from January 2008 to April 2012 were selected and treated with neoadjuvant chemotherapy(taxol combined with carboplatin) for 1-3 courses of treatment,the patients with significant curative effect underwent surgery.Results:After neoadjuvant chemotherapy,the diameters of cervical cancer decreased in varying degrees,the effective rate was 75%,surgery was conducted among most patients.Only few patients could not receive surgery.Conclusion:Neoadjuvant chemotherapy before surgery is safe and effective for treatment of cervical cancer of stage Ib2-IIb,which can reduce volume of cervical cancer,improve operative resection rate and curative efficacy,provide surgical opportunity for the patients who can't receive surgery,so it is an effective therapeutic method for the disease.