| 淋巴母细胞性NK／T细胞淋巴瘤与EB病毒的关系 |
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| 引用本文： | 李百周 何妙侠 等. 淋巴母细胞性NK／T细胞淋巴瘤与EB病毒的关系[J]. 遵义医学院学报, 2000, 23(4): 306-307 |
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| 作者姓名： | 李百周 何妙侠 等 |
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| 作者单位： | 遵义医学院病理学教研室，遵义563003 |
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| 摘 要： | 目的 探讨淋巴母细胞性NK/T细胞淋巴瘤与EB病毒的关系。方法 收集5例母细胞性NK/T细胞淋巴瘤，1例原发于鼻腔，4例原发于淋巴结。用免疫组织化学SP法确定瘤细胞本质，用原位杂交法检测EB病毒编码的RNA（EBER1/2）。结果 原发于鼻腔的1例EBER1/2呈阳性，原发于淋巴结的4例EBER1/2均阴性。EB病毒潜伏膜蛋白（LMP-1）全部阴性。结论 EBV在母细胞性NK/T细胞淋巴瘤的发生中可能具有一定作用。
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| 关 键 词： | 淋巴细胞性淋巴瘤 T细胞 自然杀伤细胞 EB病毒 |
The study of the relationship between lymphoblastic NK/T cell lymphomas and Epstein-Barr virus |
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| Li Baizhou,He Miaoxia and Tang Wentai. The study of the relationship between lymphoblastic NK/T cell lymphomas and Epstein-Barr virus[J]. Acta Academiae Medicine Zunyi, 2000, 23(4): 306-307 |
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| Authors: | Li Baizhou He Miaoxia Tang Wentai |
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| Affiliation: | Li Baizhou,He Miaoxia and Tang Wentai Department of Pathology,Zunyi Medical College,Zunyi 563003 |
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| Abstract: | Objective To explore the relationship between lymphoblastic NK/T cell lymphomas and Epstein Barr virus(EBV). Methods 5 cases of lymphoblastic NK/T cell lymphomas were collected ,4 cases from lymph nodes and 1 case from nasal cavity, the nature of neoplastic cells was confirmed by immunohistochemistry. EBV encoded RNA (EBER1/2) were detected by in situ hybridization (ISH). Results EBER1/2 were detected in 1 case lymphoblastic NK/T cell lymphoma from nasal cavity, 4 cases from lymph nodes were EBV negative. EBV latent membrane protein (LMP 1) were detected in none of 5 cases. Conclusions EBV might be a role in the pathogenesis of lymphoblastic NK/T cell lymphomas. |
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| Keywords: | iymphoblastic lymphoma T cell natural killer cell Epstein Barr virus |
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