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Role of BRCA2 mutation status on overall survival among breast cancer patients from Sardinia |
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| Authors: | Mario Budroni Rosaria Cesaraccio Vincenzo Coviello Ornelia Sechi Daniela Pirino Antonio Cossu Francesco Tanda Marina Pisano Grazia Palomba Giuseppe Palmieri |
| Affiliation: | (1) Registro Tumori di Sassari, ASL 1, Sassari, Italy;(2) Dipartimento Prevenzione, ASL BA1, Bari, Italy;(3) Istituto di Anatomia Patologica, Universit? di Sassari, Sassari, Italy;(4) Unit? Genetica dei Tumori, Istituto di Chimica Biomolecolare-CNR, Sassari, Italy |
| Abstract: | BackgroundGermline mutations in BRCA1 or BRCA2 genes have been demonstrated to increase the risk of developing breast cancer. Conversely, the impact of BRCA mutations on prognosis and survival of breast cancer patients is still debated. In this study, we investigated the role of such mutations on breast cancer-specific survival among patients from North Sardinia. |
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