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重组链激酶治疗急性脑梗死出凝血功能的动态变化
引用本文:马端,高辉,宗俊学,刘培强,许延路.重组链激酶治疗急性脑梗死出凝血功能的动态变化[J].中国实用内科杂志,2000,20(7):403-404.
作者姓名:马端  高辉  宗俊学  刘培强  许延路
作者单位:山东省血栓病研究中心,济南,250031
摘    要:】 Objective To observe the changes of hemostatic function in 24 hours in patients with acute cerebral infarction treated with 1,000,000IU of recombinant streptokinase(r-SK).Method Sixty selected patients were divided into r-SK group and control group and their PT,APTT,TT,Fg,AT-ⅢAg and AT-ⅢA were surveyed.Results After r-SK treatment,the patients' PT,TT and APTT prolonged,Fg and AT-ⅢA decreased and all of them had statistical significances compared with controls.The changes lasted for 24 hours.Conclusion Although the dosage of r-SK could affect the hemostatic function of patients,the range and duration are limited.From this point of hemostasis,this dosage of r-SK is safe in treating early stage of acute cerebral infarction.

关 键 词:重组链激酶  急性脑梗死  治疗  出凝血功能  动态变化

Kinetic changes of hemostatic function in patients with acute cerebral infarction treated by r-SK in 24 hours
Ma Duan,Gao Hui,Zong Junxue,et al..Kinetic changes of hemostatic function in patients with acute cerebral infarction treated by r-SK in 24 hours[J].Chinese Journal of Practical Internal Medicine,2000,20(7):403-404.
Authors:Ma Duan  Gao Hui  Zong Junxue  
Institution:Ma Duan,Gao Hui,Zong Junxue,et al.Shandong Research Center for Thrombotic Diseases,Ji'nan,250031
Abstract:
Keywords:Recombinant streptokinase  Acute cerebral infarction  Treatment  Hemostatic function  Kinetic change
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