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Impact of an electronic medical record reminder on hepatitis B vaccine initiation and completion rates among insured adults with diabetes mellitus
Authors:Rulin C Hechter  Lei Qian  Yi Luo  Deborah S Ling Grant  Roger Baxter  Nicola P Klein  Karen Valdez Nunley  Laurie Aukes  Cosmina Hogea  Girishanthy Krishnarajah  Brandon J Patterson  Theresa M Im  Hung Fu Tseng
Institution:1. Kaiser Permanente Southern California, 100 S. Los Robles, 2nd Floor, Pasadena, CA 91101, USA;2. Kaiser Permanente Northern California, 1 Kaiser Plaza, 16th Floor, Oakland, CA 94612, USA;3. GSK, 5 Crescent Drive, Philadelphia, PA 19112, USA
Abstract:

Objective

The Advisory Committee on Immunization Practices recommends Hepatitis B (HepB) vaccine for previously unvaccinated adults <60?years with diabetes mellitus. This observational retrospective cohort study assessed the impact of implementing electronic provider reminders on HepB vaccine initiation and 3-dose series completion rates among insured adults with diabetes aged 19–59?years old.

Research design and methods

Difference-in-difference (DID) analyses compared changes in vaccine initiation and completion rates (ratio of the rate ratio RRR] and 95% confidence interval CI]) during 12?months pre- and post-implementation between intervention and control sites. We examined trends in vaccine initiation and completion rates by plotting monthly rates during the study period. We also calculated the overall HepB vaccine coverage rates with 95% CI among all adults with diabetes aged 19–59?years old at the start and end date of the study period.

Results

Baseline HepB vaccine initiation and completion rates were similar at both the intervention and control sites. Gender, age, and race/ethnicity distributions within both sites were similar during the 12?months pre- and post-implementation. DID analyses demonstrated statistically significant differences in the changes of the annual vaccine initiation rates (RRR: 70.7, 95% CI: 62.8–79.6) and the third dose completion rates (RRR?=?18.7, 95% CI: 14.2–24.8) between the two sites. The coverage increased significantly at the intervention site while it remained low at the control site.

Conclusions

Use of provider reminders is highly effective in increasing both HepB vaccine initiation and series completion rates among adults with diabetes.
Keywords:Hepatitis B  Vaccination  Coverage  Electronic reminder  Compliance  Diabetes  ACIP  Advisory Committee on Immunization Practices  CI  confidence interval  DID  difference-in-difference  EMR  electronic medical record  HepB  hepatitis B  HBV  hepatitis B virus  ICD-9  International Classification of Diseases – Ninth Revision  KP  Kaiser Permanente  KPNC  Kaiser Permanente Northern California  KPSC  Kaiser Permanente Southern California  MCO  managed care organization  NHANES  National Health and Nutrition Examination Surveys  RR  rate ratio  RRR  ratio of rate ratio  US  United States
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