早发性卵巢功能不全对骨代谢影响

早发性卵巢功能不全（POI）患者会发生骨质疏松、脂代谢异常及心血管疾病。骨质疏松症的发生严重影响人们身体健康和生存质量，已成为一个全球性的公众健康问题。对于年轻POI患者，如果能充分认知并早期预防和早期治疗，可以控制或减缓病程的发展。文章以POI患者体内激素变化特点为出发点，阐述各激素变化影响骨代谢机制，以便加强对骨健康管理。

Effects of premature ovarian insufficiency on bone metabolism

Osteoporosis，lipid metabolic abnormalities and cardiovascular diseases are present in POI patients.Osteoporosis has seriously affected people's health and quality of life，and has become a global public health problem.For young POI patients，the development of the disease can be controlled or slowed down if adequate cognition，early prevention and early treatment are made.In this paper，the changes of hormones in POI patients were taken as the starting point，and the mechanism of bone metabolism influenced by the changes of hormones was discussed，so as to strengthen the management of bone health.