SD-Ag和MEBO调合剂治疗深Ⅱ度感染创面与单独用药的比较研究

目的研究和探索不同外用药对深Ⅱ度感染创面的治疗效果。方法磺胺嘧啶银(SD-Ag)粉和MEBO调合剂治疗深Ⅱ度感染创面200例,采用SD-Ag乳膏治疗230例,单独外用MEBO治疗210例。结果 SD-Ag粉和MEBO调合剂治疗组伤后平均愈合时间(26±5.0)d,4例深Ⅱ度创面转为Ⅲ度肉芽创面;MEBO治疗组伤后平均愈合时间(30±4.5)d,12例深Ⅱ度创面转为Ⅲ度肉芽创面,SD-Ag治疗组伤后平均愈合时间(35±5.6)d,30例深Ⅱ度创面转归为Ⅲ度肉芽创面。三组患者在自愈率和创面转归上存在统计学差异(P<0.05)。结论较单独外用MEBO、SD-Ag乳膏治疗深Ⅱ度烧烫伤感染创面,SD-Ag与MEBO调合治疗能有效缩短创面愈合时间,减少残余肉芽创面转归。

SD-Ag and MEBO mixture or single effect on infective deep Ⅱ degree burn wonds: Comparative study

Objective To investigate treatmen effect of different topical drug for the infective deep Ⅱ degree wounds.Methods The 200 cases were treated with SD-Ag powder and MEBO mixture,230 cases with SD-Ag cream,210 cases with MEBO alone.Results The SD-Ag powder and MEBO mixture group's average healing time was(26±5.0) days,4 of them vesting to the Ⅲ degree granulation tissues.The MEBO group's average heeding time was(30 ±4.5) days,12 of them vesting to the Ⅲ degree granulation tissue.The SD-Ag group's healing time was 35±5.6 days,30 of them vesting to Ⅲ degree wound.There were significant differences among the three groups(P<0.05).Conclusion The mixture of SD-Ag powder and MEBO can shorten wound healing time and reduce the residual granulation vesting in the treatment of infective deep Ⅱ degree burn wounds compared with to SD-Ag or MEBO alone.