| 酮替芬对感染伯氏疟原虫小鼠血清维生素A,C,E含量的影响 |
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| 引用本文： | 邬大元,王静,陈鸿基,翁幼萍. 酮替芬对感染伯氏疟原虫小鼠血清维生素A,C,E含量的影响[J]. 福建医科大学学报, 1992, 0(2) |
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| 作者姓名： | 邬大元 王静 陈鸿基 翁幼萍 |
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| 作者单位： | 福建医学院生化中心实验室，福建医学院寄生虫学教研室，福建医学院卫生系，福建医学院卫生系 |
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| 摘 要： | 采用荧光分光光度法和紫外分光光度法测定感染伯氏疟原虫(P.b,ANKA株)小鼠血清中维生素A,C,E含量。感染未治组小鼠血清V.A,V.C含量明显低于酮替芬组、酮替芬+氯喹组及正常组,与氯喹组无显著差异,酮替芬及酮替芬+氯喹组的小鼠血清中V.A,V.C含量与正常组无显著差异。各组V.E无显著差异。
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| 关 键 词： | 酮替芬 疟原虫 氯喹 维生素A 维生素C 维生素E |
Effect of Ketolfen on Serum Vitamin A, C, E in Mice Infected with P. Berghei |
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| Wu Dayuan,Wang Jing,Chen Hongji Biochemistry Central Lab.,Fujian Medical College,Fuzhou. Effect of Ketolfen on Serum Vitamin A, C, E in Mice Infected with P. Berghei[J]. Journal of Fujian Medical University, 1992, 0(2) |
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| Authors: | Wu Dayuan Wang Jing Chen Hongji Biochemistry Central Lab. Fujian Medical College Fuzhou |
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| Abstract: | Using fluorecent and visible ultraviolet spectrometries, a comparative study of the V. A, V. E, V. C contents in the sera of mice infected with Plasmidium berghei and treated with ketolfen and chloroquine was made. The results showed that there was no statistically significant difference in V. E content among them (P>0. 05) ,but the V. A and V. C contents were significantly lower in infected mice than in the others (P<0. 01), except the mice treated with chloroquine only(P>0. 05). The V. A and V. C con- tents in infected mice had no obviously difference after treatment with ketolfen and chloroquine and were in the normal level. The relation of V. A and V. C contents in the sera of mice between the infection and treatment with antiplasmodial drug is worthy to be studied further. |
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| Keywords: | ketolfen plasmodium chlorquine vitamin A vitamin C vitamin E serum |
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