夹脊穴直刺配合臭氧穴位注射治疗急性带状疱疹神经痛疗效观察

目的探讨夹脊穴直刺配合臭氧穴位注射联合阿昔洛韦治疗中老年急性带状疱疹神经痛的临床疗效。方法采用前瞻性、随机对照试验的设计,52例急性带状疱疹神经痛患者随机分为两组,对照组服用阿昔洛韦每次0.6～0.8 g,4～5次.d-1,服7～10 d;治疗组在上述服用阿昔洛韦的基础上同时采用夹脊穴直刺配合臭氧穴位注射治疗,注射臭氧浓度25 mg.L-1,3～4 d治疗1次,治疗4～6次。使用疼痛的VAS评分、控制皮疹时间及后遗神经痛发生率评价疗效。结果治疗后1、7、30与60 d,治疗组VAS评分明显低于同期对照组(P<0.05);治疗后30 d及60 d,对照组和治疗组VAS评分与治疗前自身比较,差异均有统计学意义(P<0.05)。治疗组止疱时间和结痂时间分别是(3.23±1.12)d和(4.03±0.96)d,低于对照组的(5.36±1.89)d和(5.63±1.55)d,两组比较差异有统计学意义(P<0.05);治疗组总优良率(76.0%)高于对照组(38%),差异有统计学意义(P<0.05)。两组均未见严重不良反应发生。结论夹脊穴直刺配合臭氧穴位注射联合阿昔洛韦治疗中老年急性带状疱疹神经痛可以及时控制病情,迅速缓解疼痛,并能减少后遗神经痛的发生率。

Efficacy Observation of Acute Herpetic Neuralgia Treated with Perpendic- ular Puncture at Jiaji Points and Ozone Acupoint Injection

Objective To discuss the clinical efficacy on acute herpetic neuralgia in the middle and aged patients treated with perpendicular puncture at Jiaji points, combined with ozone aeupoint injection and medication of Acyelovir. Methods A prospective random controlled trial was designed. 52 cases of acute herpetic neuralgia were randomized into two groups. In a control group, Acyclovir was prescribed for oral ad- ministration,0.6 -0.8 g,4 -5 times· d-1 ,for 7- 10 days. In an observation group,on the basic medication of Acyclovir as the control group, the perpendicular puncture at Jiaji points, combined with ozone acupoint in- jection was adopted,25 mg · L-1 ,3 - 4 day treatment as one session, for 4 - 6 sessions required. VAS score, skin rash control time and the incidence of post - herpetic neuralgia were used for the efficacy assessment. Results In 1,7,30 and 60 days after treatment, VAS score in the observation group was lower apparently than that in the control group in the same time phase （ P 〈 0.05 ）. In 30 days and 60 days after treatment, in the self - comparison with that before treatment, the differences in VAS score were significant statistically in both control group and observation group（ P 〈 0.05 ）. The time of zoster - relief time and scarring time was （3.23 ± 1.12）d and（4.03 ±0.96） d in the observation group,which was lower than（5.36 ± 1.89） d and （ 5.63 ± 1.55 ） d in the control group separately, presenting the statistically significant difference in compari- son between two groups （ P 〈 0.05 ）. The total excellent rate （ 76.0% ） in the observation group was higher than that（ 38% ）in the control group ,presenting the statistically significant difference（ P 〈 0.05 ）. The severe adverse reaction was not found in two groups. Conclusion The therapy of perpendicular puncture at Jiaji points, combined with ozone acupoint injection and medication of Acyclovir controls the sickness timely, re- lieves pain rapidly and reduces the incidence of post - herpetic neuralgia in the treatment of acute herpetic neuralgia in middle and aged patients.