Cellular profile of the peritumoral inflammatory infiltrate in squamous cells carcinoma of oral mucosa: Correlation with the expression of Ki67 and histologic grading |
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| Authors: | Fabricio LD Vieira Beatriz J Vieira Marco AM Guimaraes Fernando M Aarestrup |
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| Affiliation: | 1.UERJ, Rio de Janeiro, RJ Brazil,Dom André Arcoverde Foundation,Valen?a/RJ,Brazil;2.Dom André Arcoverde Foundation,Valen?a/RJ,Brazil;3.Laboratory of Immunopathology and Experimental Pathology-CBR UFJF,Juiz de Fora,Brazil;4.Dentistry School of UFJF,Juiz de Fora,Brazil;5.UERJ,Rio de Janeiro,Brazil;6.Laboratory of Immunopathology and Experimental Pathology-CBR UFJF,Juiz de Fora,Brazil;7.Dentistry School of UFJF,Juiz de Fora, MG Brazil, Dom André Arcoverde Foundation,Valen?a/RJ,Brazil |
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| Abstract: | Background Squamous cells carcinoma is the most important malignant tumor with primary site in the oral cavity and, given the great exposure of mucosa and lips to the etiologic factors of this neoplasm, its incidence is high. Investigation of the prognostic determinants is significant for the expectations of treatment proposal and cure of the patient. The local immune response represented by peritumoral inflammatory infiltrate is a possible prognostic factor. |
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