银川市结核发病危险因素病例对照研究

目的 分析银川市结核病发病危险因素,为结核病预防提供参考依据.方法 选取119例结核病患者为病例组,选取179例体检人员为对照组进行结核病发病危险因素病例对照研究,进行单因素和非条件logistic回归多因素分析.结果 单因素分析表明:文化程度(χ2=2.363,P=0.018)、月人均收入(χ2=3.040,P=0.002)、吸烟史(χ2=2.500,P=0.012)、健身活动(χ2=2.330,P=0.020)、卡介苗接种史(χ2=22.151,P=0.000)、结核接触史(χ2=15.740,P=0.000)与结核病发生显著相关.多因素分析中月人均收入、吸烟史、健身活动、卡介苗接种史、结核接触史等因素进入方程模型(χ2值分别为5.880,7.368,3.891,21.127,14.536;OR值分别为0.529,1.571,0.774,0.264,3.978;P值均＜0.05).结论 结核接触史、吸烟史是银川市结核发病的危险因素.月人均收入高、接种卡介苗、多参加健身活动是银川市结核发病的保护因素.

A case-control study on risk factors for tuberculosis in Yinchuan city

OBJECTIVE: To study the risk factors of tuberculosis in Yinchuan city and lay a basis for its prevention and control. METHODS: A matched case-control (119:179) study for the risk factors was carried out. Data were analyzed with single-variable analysis and multiple factor logistic regression analysis. RESULTS: Single-variable analysis showed that the education background (chi2 = 2.363, P = 0.018), family economic income (chi2 = 3.040, P = 0.002), smoking (chi2 = 2.500, P = 0.012), physical activities (chi2 = 2.330, P = 0.020), bacille Calmette-Guerin (BCG) vaccination history (chi2 = 22.151, P = 0.000), history of exposure to tuberculosis (chi2 = 15.740, P = 0.000) and so on had significant effects on tuberculosis. Multiple logistic regression analysis showed that family monthly income, smoking, physical activity, BCG vaccination history, history of exposure to tuberculosis entered the final regression model (chi2 = 5.880, 7.368, 3.891, 21.127, 14.536; OR = 0.529, 1.571, 0.774, 0.264, 3.978; P < 0.05). CONCLUSION: History of exposure to tuberculosis and smoking should be the risk factors of tuberculosis in Yinchuan. Having much income, physical activities, and BCG vaccination history should be the preventive factors.