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| Meta分析结合病例报道进行艾滋病合并生殖器疱疹的耐药研究 | |
| 引用本文： | 陆珍珍,邓鑫,刘振威. Meta分析结合病例报道进行艾滋病合并生殖器疱疹的耐药研究[J]. 中国性科学, 2014, 0(2): 68-71 |
| 作者姓名： | 陆珍珍 邓鑫 刘振威 |
| 作者单位： | 广西中医药大学附属瑞康医院艾滋病研究中心,南宁530011 |
| 基金项目： | 国家中医药管理局临床研究基地课题（JDZX2012022）;广西壮族自治区科技厅科技攻关课题（11107009-1-3,1298003-1-1）;广西壮族自治区卫生厅课题（2012032,GZZY13-22）. |
| 摘 要： | 生殖器疱疹(GH)已经跃升为全球第三大性传播疾病,艾滋病患者(本文为HIV-1阳性患者)合并GH感染率高达50%~90%。常规的阿昔洛韦类治疗GH在普通人群中的耐药率低于1%,在HIV-1(+)患者中明显升高达4.2%~7.1%。通过分析两个HIV患者中耐药GH的临床病例,给HIV合并耐药GH的诊疗提供参考,揭示HIV患者中发生耐药GH面临的挑战。 |
| 关 键 词： | 艾滋病 生殖器疱疹 耐药 |
Drug Resistance of genital herpes simplex in HIV/AIDS patients |
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| LU Zhenzhen,DENC Xin,LIU Zhenwei. Drug Resistance of genital herpes simplex in HIV/AIDS patients[J]. The Chinese Journal of Human Sexuality, 2014, 0(2): 68-71 | |
| Authors: | LU Zhenzhen DENC Xin LIU Zhenwei |
| Affiliation: | . AIDS Research Center, Rui Kang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning 530011, China |
| Abstract: | Genital herpes simplex （GH） has been up to the 3rd lead of sexual transmitted disease worldwide. 50% -90% HIV - 1 infected patients were co - infected with GH. Acyclovir therapy resistance among GH immunocompetent patients has remained lower than 1%, but the resistance rate among HIV patients were much higher： 4.2% -7.1%. The paper reviewed two cases of Acyclovir resistant HIV - 1 positive patients infected by GH to describe the atypical features and to reveal the challenges we are facing in the treatment for HIV/HSV co - infected patient. |
| Keywords: | HIV Genital herpes simplex Resistant |
| 本文献已被 CNKI 维普 等数据库收录！ | |