FSH治疗特发性少、弱精子症的临床疗效观察

目的:观察纯尿促卵泡素(FSH)治疗特发性少弱精子症的疗效,并对其有效性、安全性进行观察.方法:2011年6月~2012年3月间在山东中医药大学第二附属医院生殖医学科,根据WHO推荐的诊断标准采用计算机辅助精液分析系统等方法筛选100例男性不育患者中的少弱精子症人群,采用纯FSH 75IU,每3d一次肌肉注射,疗程3个月.采用自身前后对照的方法,以a、b级精子和精子活动率(a+b+c)为指标,评价FSH的疗效.结果:应用FSH的病例较治疗前a、b级精子和精子活动率(a+b+c)均显著升高(P<0.05).结论:纯FSH治疗男性特发性少弱精子症可改善患者的精液质量,并无不良反应.

Clinical efficacy of FSH in the treatment for idiopathic oligospermia and asthenospermia

Objectives: To observe the clinical efficacy of pure urinary follicle stimulating hormone(FSH) in the treatment for idiopathic oligospermia and asthenospermia.The effectiveness and safety of pure FSH were also evaluated.Method: From June 2011 to March 2012,according to the WHO recommended diagnostic criteria,computer-assisted semen analysis system was used to screen for 100 cases of male infertility patients with oligospermia and asthenospermia to form a sample in the department of reproductive medicine of the Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine.Patients were treated by intramuscular injection with pure FSH 75IU once every 3 days,for a course of 3 months.The efficacy of FSH was assessed before and after the treatment with a,b sperm and sperm mobility(a+b+c) as the index.Result: In terms of a,b sperm and sperm mobility(a+b+c),the efficacy after the treatment with FSH was significantly better than that before the treatment(P<0.05).Conclusion: The treatment with pure FSH for patients with idiopathic oligospermia and asthenospermia could improve semen quality and had little adverse effects.