| 人工髓核材料(半晶聚乙烯醇水凝胶弹性体)的研制 |
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| 引用本文： | 顾正秋,马远征,高瑾,刘建涛,李永.人工髓核材料(半晶聚乙烯醇水凝胶弹性体)的研制[J].生物医学工程学杂志,2004,21(3):347-349. |
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| 作者姓名： | 顾正秋 马远征 高瑾 刘建涛 李永 |
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| 作者单位： | 1. 北京科技大学,材料科学与工程学院,北京,100083
2. 解放军309医院,骨科,北京,100091 |
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| 基金项目： | 国家自然科学基金资助项目 ( 5 9775 0 3 8) |
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| 摘 要： | 研制一种可替代椎间盘髓核并恢复其功能的生物医用材料 ,探讨半晶聚乙烯醇水凝胶弹性体材料临床应用的可行性。聚乙烯醇 (PVA)水溶液在 - 2 0℃下冷冻 6～ 12 h,室温下融化 1～ 2 h,上述过程重复 1～ 3次 ,然后对试样进行真空脱水 ,制得人工髓核材料 (半晶 PVA水凝胶弹性体 )。差示扫描量热法 (DSC)和力学性能试验研究了 PVA水溶液浓度、真空脱水和 γ射线辐照对水凝胶 PVA的结晶度和力学性能的影响
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| 关 键 词： | 人工髓核材料 聚乙烯醇水凝胶 弹性体 |
Development of Artificial Disc Nucleus Materials (Semicrystalline Polyvinyl Alcohol Hydrogel Elastomers) |
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| Gu Zhengqiu,Ma Yuanzheng,Gao Jin,Liu Jiantao,Li Yong.Development of Artificial Disc Nucleus Materials (Semicrystalline Polyvinyl Alcohol Hydrogel Elastomers)[J].Journal of Biomedical Engineering,2004,21(3):347-349. |
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| Authors: | Gu Zhengqiu Ma Yuanzheng Gao Jin Liu Jiantao Li Yong |
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| Institution: | School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China. |
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| Abstract: | For the purpose of developing of disc nucleus replacement (semicrystalline PVA hydrogel elastomers) and explorating the possibility of clinical application, in this study,the aqueous PVA solution froze at -20 degrees C for 6-12 h, and then thawed at room temperature for 1-2 h. The same process was repeated 1-3 times. After the specimen was dehydrated in vacuum, a kind of artificial disc nucleus materials (semicrystalline PVA hydrogel elastomers ) was formed. DSC and mechanical tests were conducted to investigate the influence of aqueous PVA solution concentration, of dehydrating in vacuum, and of gamma-ray irradiating upon the degree of crystallity and mechanical properties of PVA hydrogel elastomers. |
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| Keywords: | Artifiical disc nucleus materials PVA hydrogel Elastomers |
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