浙江省瑞安地区育龄妇女孕前6种感染性病原体血清学调查分析

目的 了解浙江省瑞安地区育龄妇女孕前6种感染性病原体的感染情况,为本区域妇女保健和优生优育工作提供实验依据。 方法 采用酶联免疫吸附试验(ELISA)对4153名育龄妇女联合检测乙型病毒性肝炎(乙肝)表面抗原(HBsAg)、梅毒螺旋体抗体(抗-TP)、人类免疫缺陷病毒抗体(抗-HIV1/2)及弓形虫(TOX)、风疹病毒(RV)、巨细胞病毒(CMV)相关的IgM/IgG抗体。 结果 4153名育龄妇女中,HBsAg阳性296例(7.13%);抗-TP阳性18例(0.43%);抗-HIV1/2阳性1例(0.02%);TOX、RV、CMV 3种病原体IgM抗体阳性率分别为0.29%、0.14%和0.84%,IgG抗体阳性率分别为1.13%、60.15%和89.86%。 结论 瑞安地区育龄妇女存在上述6种感染性病原体的感染,孕前检测和及时预防、有效干预有利于优生优育。

Pregestational serosurvey of 6 infections pathogens in child bearing aged women in Rui'an, Zhejiang

Objective To understand the infection status of 6 infectious pathogens in child bearing aged women before conception in Rui'an, Zhejiang province, and provide evidence for the improvement of women and children's health. Methods HBsAg, anti-TP, anti-HIV1/2 and IgM/IgG antibodies to toxoplasma, rubella virus and cytomegalovirus were detected by using ELISA in 4153 child bearing aged women. Results Among the 4153 women, 296 were HBsAg positive (7.13%), 18 were anti-TP positive (0.43%), and 1 was anti-HIV1/2 positive (0.02%); the positive rates of IgM antibodies to toxoplasma, rubella virus and cytomegalovirus were 0.29%, 0.14% and 0.84% respectively, and the positive rates of IgG antibodies to toxoplasma, rubella virus and cytomegalovirus were 1.13%, 60.15% and 89.86% respectively. Conclusion The infections of 6 above-mentioned infectious pathogens were detected among the child bearing aged women before conception in Rui'an. Pregestational detection, timely prevention and effective interventions are essential for women and children's health.