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真菌性呼吸机相关性肺炎危险因素分析
引用本文:卓婕,陈东宁,董云秋. 真菌性呼吸机相关性肺炎危险因素分析[J]. 中华医院感染学杂志, 2008, 18(12)
作者姓名:卓婕  陈东宁  董云秋
作者单位:1. 首都医科大学附属北京同仁医院呼吸内科,北京,100730
2. 首都医科大学附属北京同仁医院细菌室,北京,100730
摘    要:
目的 探讨呼吸蕈症监护病房(RICU)机械通气患者真菌性呼吸机相关性肺炎(FVAP)的易患因素和病原学特点.方法 将2005年1月-2007年6月RICU接治的37例呼吸机相关性肺炎(VAP)患者分为FVAP组和非真菌性呼吸机相关性肺炎(NFVAP)组,比较两组真菌感染的易患因素;分析FVAP组病原菌的分布特点.结果 FVAP组全身激素应用和联合应用抗菌药物比例显著大于NFVAP组(P<0.05);FVAP的例数以插管后第7~14天最多;FVAP组痰标本共培养出真菌12株,其中假丝酵母菌属10株,占83.3%(白色假丝酵母菌6株,占50.0%;热带假丝酵母菌2株,占16.7%;克柔假丝酵母菌和近平滑假丝酵母菌各1株,各占8.3%);烟曲霉菌2株,占16.7%.结论 为避免FVAP的发生应减少气管插管、缩短机械通气时间;明确感染菌株及其敏感药物,对临床选择有效的抗真菌治疗具有指导作用.

关 键 词:呼吸机相关性肺炎  真菌  危险因素

Risk Factors of Fungal Ventilator-associated Pneumonia
ZHUO Jie,CHEN Dong-ning,DONG Yun-qiu. Risk Factors of Fungal Ventilator-associated Pneumonia[J]. Chinese Journal of Nosocomiology, 2008, 18(12)
Authors:ZHUO Jie  CHEN Dong-ning  DONG Yun-qiu
Affiliation:ZHUO Jie,CHEN Dong-ning,DONG Yun-qiu(Beijing Tongren Hospital,Capital University of Medical Sciences,Beijing 100730,China)
Abstract:
OBJECTIVE To investigate the risk factors of fungal ventilator associated pneumonia(FVAP) and the characteristic of pathogenic fungi.METHODS Thirty seven VAP patients were divided into FVAP group and nonfungal ventilator associated pneumonia(NFVAP) group.Risk factors were compared between the two groups and the characteristic of pathogenic fungi was analyzed.RESULTS Compared to the NFVAP group,the FVAP group showed a significant higher rate in systemic usage of glucocorticosteriod and combined application o...
Keywords:Ventilator associated pneumonia  Fungi  Risk factor  
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