单纯性肥胖儿童血压升高相关危险因素COX回归分析

目的 筛选肥胖儿童发生血压升高的高危因素,为早期预防肥胖儿童发生高血压提供依据.方法 选择西安交通大学医学院第二附属医院儿科门诊2010年5-10月就诊的肥胖儿童124例,参照中国儿童青少年血压参照标准研制协作组2010年标准筛选血压升高儿童,分析内容包括遗传因素、早期喂养、饮食行为、学习及运动情况、家庭环境等与肥胖及血压升高相关因素.结果 共有68例肥胖儿童出现血压升高,发生率为54.84％.COX多因素分析显示,母亲肥胖、喜食肉类食品、晚上睡眠时间、午休时间、喝饮料的频率、膨化食物是与肥胖儿童发生血压升高预后的相关危险因素.结论 肥胖儿童发生血压升高的比例很高,不良饮食习惯及母亲肥胖、过长的睡眠时间均能增加血压升高发生的风险.在肥胖儿童的治疗及随访中,应减少相关危险因素的暴露,从而预防血压升高的发生.

COX regression analysis on some risk factors related to elevation of blood pressure among simple obese children

Objective To identify high-risk factors related to elevation of blood pressure among overweight children,and to provide evidence for the early prevention.Methods Among 124 overweight children(69 male and 55 female) chosen in the department of pediatrics in the Second Affiliated Hospital of Medical College of Xi’ an Jiaotong University from May to October 2010,at the age of 7-18 years(14 years on average),the patients with elevation of blood pressure were screened out by the diagnosis based on 2010 Standards from the Task force for Development of Blood Pressure Reference Standards for Chinese Children and Adolescents.Clinical data was analyzed including some factors related to obesity and elevation of blood pressure,e.g.genetic factors,early feeding,dietary behavior,learning and exercise and home environment.Results Totally 68 overweight patients had elevation of blood pressure,accounting for 54.84% in all the children.And it was demonstrated through COX multivariate analysis that the risk factors related to the prognosis for the overweight children with elevation of blood pressure included mother’s obesity level,meat foods preference,length of sleep at night,length of midday rest,frequency of having a drink and puffed foods.Conclusion There is a very high percentage of hypertension cases in the overweight children.It is revealed that bad eating habits,mother’s obesity and excessive length of sleeping are all identified as the contributors to elevation of blood pressure.Therefore,special attention should be paid to the risk factors mentioned above in the treatment and follow-up for the overweight children.In this point,reducing exposure to these risk factors helps prevent occurrence of elevation of blood pressure.