广西某高校新生乙型肝炎流行病学调查

目的了解广西某高校入学新生乙型肝炎流行病学特征,为探讨我国大学生是否需要普种乙肝疫苗或加强免疫提供参考。方法对广西某高校2009级新生1 971人进行乙肝5项标志物检测,并对结果进行统计学分析。结果 1 971名大学新生血清HBV 5项标志物(HBsAg、HBsAb、HBeAg、HBeAb和HBcAb)阳性率分别为7.36%、52.66%、0.33%、10.81%和18.62%,其中HBsAg阳性率东南地区较高、男生高于女生、农村学生高于城镇学生、汉族学生高于少数民族学生(P<0.05);有13种感染模式,以"小三阳"和"大三阳"为主要的感染模式。结论对大学新生开展传染病防治健康教育和加强HBV的免疫接种,是预防HBV感染的有效途径。

Epidemiology investigation on hepatitis B virus infection of freshmen in a college in Guangxi

Objective To understand the characteristics about epidemiology of hepatitis B virus infection of certain college freshmen in Guangxi so as to make a reference for exploring whether the college students in our country need to inoculate hepatitis B vaccine or not.Methods A total of 1 971 freshmen of grade 2009 of a college in Guangxi were investigated for detecting hepatitis B 5 markers and the results were analyzed statistically.Results The positive rates of the students’ serum markers(HBsAg,HBsAb,HBeAg,HBeAb and HBcAb) were 7.36%,52.66%,0.33%,10.81% and 18.62% respectively,of which,the positive rate of HBsAg was higher in the southeast area than that in other areas,in boys than in girls,in the students living country area than those living city,and in Han national students than minority students(P<0.05).There were 13 kinds of infection patterns,of which,"HBsAg+/HBeAb+/HBcAb+" and "HBsAg+/HBeAg+/HBcAb+" were the two main infection patterns.Conclusions The most effective way to prevent HBV infection is to carry out health education on prevention of infectious diseases and inoculate hepatitis B vaccine among students.