| 丙烯酰胺中毒大鼠神经组织及血清中Na~+、K~+、Ca~(2+)离子的变化 |
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| 引用本文： | 吕京 崔涛. 丙烯酰胺中毒大鼠神经组织及血清中Na~+、K~+、Ca~(2+)离子的变化[J]. 卫生研究, 1989, 18(3): 5-6 |
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| 作者姓名： | 吕京 崔涛 |
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| 作者单位： | 中国预防医学科学院劳动卫生与职业病研究所，中国预防医学科学院劳动卫生与职业病研究所，中国预防医学科学院劳动卫生与职业病研究所，中国科学院科学仪器厂 |
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| 摘 要： | 用高分辨质谱计测定丙烯酰胺中毒大鼠神经组织及血清中Na~+、K~+、Ca~(2+)离子的变化,结果表明:急性中毒时,小脑中三种离子的含量均明显下降(P<0.05);亚急性中毒时,血清中K~+明显下降(P<0.05)。
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| 关 键 词： | 离子 丙烯酰胺 神经 血清 |
Study on Na~ , K~ , Ca~( )Concentrations in Rat Nervous Systems and Blood Serum after Exposure to Acrylamide |
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| Abstract: | In this study, a new type of mass spectrometer with high quality(Type ZHP 5A) was used for measuring Na~ , K~ , Ca~( )concentrations at the same tlme.The results showed: 1.After single exposure to Acrylamide(300 mg/kg), the Na~ , K~ ,Ca~( )concentrations in rat cerebellum were decreased significantly(p<0.05)and no significant changes in cerebrum and sciatic nerve or in blood serum were observed;2.After multiple exposures to Acrylamide(10 or 50mg/kg, once per day, 12 days, ip), the K~ concentration was decreased significantly in blood serum. |
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| Keywords: | ion acrylamide nervous systems blood serum |
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