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循环DNA、循环肿瘤细胞端粒酶与肿瘤早期诊断
引用本文:Zhang Z,Yuan Y. 循环DNA、循环肿瘤细胞端粒酶与肿瘤早期诊断[J]. 癌症, 2004, 23(2): 227-229
作者姓名:Zhang Z  Yuan Y
作者单位:中国医科大学附属第一医院肿瘤研究所,辽宁,沈阳,110001;中国医科大学附属第一医院肿瘤研究所,辽宁,沈阳,110001
摘    要:肿瘤患者循环DNA水平的增高、肿瘤特征性基因改变及循环肿瘤细胞端粒酶活性的表达,不仅可出现在肿瘤的晚期,也可发生在肿瘤的早期阶段。循环DNA和肿瘤细胞端粒酶的联合检测,对于肿瘤早期诊断有重要意义。

关 键 词:循环DNA  循环肿瘤细胞  端粒酶  肿瘤  诊断
文章编号:1000-467X(2004)02-0227-03
修稿时间:2002-12-05

Circulating DNA, telomerase of circulating tumor cells and early diagnosis of tumors
Zhang Zhong,Yuan Yuan. Circulating DNA, telomerase of circulating tumor cells and early diagnosis of tumors[J]. Chinese journal of cancer, 2004, 23(2): 227-229
Authors:Zhang Zhong  Yuan Yuan
Affiliation:Cancer Institute of The First Hospital, China Medical University, Shenyang, Liaoning, PR China.
Abstract:The increase of circulating DNA levels, the mutations of tumor characteristic genes and the telomerase expression of circulating tumor cells can be detected not only in advanced stage but also in early stage of tumors. The combinational detection of circulating DNA and telomerase of circulating tumor cells is useful for the early diagnosis of tumors.
Keywords:Circulating DNA  Circulating tumor cells  Telomerase  Tumor  Diagnosis  
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