| 蜂蛇胶囊对荷瘤小鼠的抗肿瘤作用 |
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| 引用本文： | 曲爱兵,赵维诚,赵岩. 蜂蛇胶囊对荷瘤小鼠的抗肿瘤作用[J]. 中华肿瘤防治杂志, 2004, 11(1): 32-34 |
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| 作者姓名： | 曲爱兵 赵维诚 赵岩 |
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| 作者单位： | 辽宁省肿瘤研究所,辽宁,沈阳,110042;辽宁省肿瘤防治办公室,辽宁,沈阳,110042 |
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| 基金项目： | 辽宁省科委科技攻关项目(2001225001-13) |
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| 摘 要： | 目的 :验证蜂蛇胶囊对小鼠H2 2 肝癌和小鼠肉瘤 180 (S180 )的抑制作用及小鼠艾氏腹水癌的生命延长作用。方法 :荷瘤小鼠灌胃给药 14d后处死称瘤重 ,计算抑瘤率 ,艾氏腹水癌计算生存期延长率。结果 :蜂蛇胶囊对小鼠H2 2肝癌和小鼠S180有较强的抑制作用 ,对艾氏腹水癌有生命延长作用 ,抑瘤率 >3 0 % ,生命延长率 >5 0 % ,3次实验重现性较好。结论 :该药对实体瘤和腹水癌疗效稳定 ,抑瘤作用较强 ,有延长生命的作用。
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| 关 键 词： | 肿瘤 实验性/中药疗法 抗肿瘤药(中药)/治疗应用 肿瘤细胞 培养的 |
| 文章编号： | 1009-4571(2004)01-0032-03 |
| 修稿时间： | 2003-04-14 |
Antineoplastic effect of Fengshe capsule on mice carrying tumor |
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| QU Ai bing ,ZHAO Wei cheng ,ZHAO Yan .Liaoning Tumor Institute,Shenyang ,P.R.China .Liaoning Tumor Prevention and Treatment Office,Shenyang ,P.R.China. Antineoplastic effect of Fengshe capsule on mice carrying tumor[J]. Chinese Journal of Cancer Prevention and Treatment, 2004, 11(1): 32-34 |
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| Authors: | QU Ai bing ZHAO Wei cheng ZHAO Yan .Liaoning Tumor Institute Shenyang P.R.China .Liaoning Tumor Prevention Treatment Office Shenyang P.R.China |
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| Affiliation: | QU Ai bing 1,ZHAO Wei cheng 1,ZHAO Yan 2 1.Liaoning Tumor Institute,Shenyang 110042,P.R.China 2.Liaoning Tumor Prevention and Treatment Office,Shenyang 110042,P.R.China |
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| Abstract: | OBJECTIVE:To verify the inhibition of Fengshe capsule for mice bearing sarcoma S180,H 22 and the survival time of mice bearing ascites.METHODS:Fengshe capsule was administrated by ig for a course of 14 consecutive days and the anti tumor effect of the drug detected.RESULTS:Fengshe capsule remarkably inhibited the growth of tumor and prolonged the life span of mice with tumor.The rate of anti tumor was >30%,the rate of prolonged life >50%.The tests recurred thrice.CONCLUSIONS:Fengshe capsule has anti tumor effects and can extend the survival time of mice carrying tumor. |
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| Keywords: | neoplasms experimental/drug therapy(TCD) antineoplastic drugs(TCD)/therapeutic use tumor cells cultured |
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