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| 冠状动脉支架置入后血管再狭窄的危险因子 | |
| 引用本文： | 尚跃丰,王文欣,王佩显. 冠状动脉支架置入后血管再狭窄的危险因子[J]. 中国组织工程研究与临床康复, 2009, 13(13): 2597-2600. DOI: 10.3969/j.issn.1673-8225.2009.13.044 |
| 作者姓名： | 尚跃丰 王文欣 王佩显 |
| 作者单位： | 1. 天津市天和医院急诊科,天津市,300050 2. 天津医科大学总医院心内科,天津市,300070 |
| 摘 要： | 冠状动脉粥样硬化性心脏病危险因素、血管造影下冠状动脉病变特征、支架置入操作技术参数是影响冠状动脉病变支架置入后再狭窄的主要危险因子.这些危险因子在不同的组合条件下可对支架置入后再狭窄产生不同的影响.目前研究结果较一致的可增加支架置入后再狭窄危险的因素为:冠状动脉病变长度、病变血管直径<3 mm、开口病变、支架总长度以及置入支架的个数.同样研究结果较一致的足:药物洗脱支架(紫杉醇药物洗脱支架和雷帕霉素药物洗脱支架)与裸金属支架相比,明显降低了发生支架置入后再狭窄的危险;而这2种药物洗脱支架之间相比,雷帕霉素药物洗脱支架在降低支架置入后再狭窄风险方面似乎优于紫杉醇药物沈脱支架.而其他的一些危险因素,如年龄、性别、吸烟、高血压等目前的研究结果并不一致. |
| 关 键 词： | 危险因子 冠状动脉再狭窄 支架置入 综述文献 |
Risk factors of restenosis after coronary artery stent implantation |
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| Shang Yue-feng,Wang Wen-xin,Wang Pei-xian. Risk factors of restenosis after coronary artery stent implantation[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2009, 13(13): 2597-2600. DOI: 10.3969/j.issn.1673-8225.2009.13.044 | |
| Authors: | Shang Yue-feng Wang Wen-xin Wang Pei-xian |
| Abstract: | The risk factors of coronary artery disease, angiographic and procedural features are the main risk factors of restenosis after coronary artery stent implantation. In different combinations, these risk factors have different effects on coronary restenosis. The risk factors that the results of trials were more consistent include coronary lesion length, lesion vessel diameter <3 mm, ostial disease, total stent length, and number of stent. The same results of trials as stated above indicated that drug-eluting stent (sirolimus-eluting stent and paclitaxel-eluting stent), compared with bare-metal stent, significantly decreased the risk of restenosis. Compared these two drug-eluting stent, sirolimus-eluting stent was superior to paclitaxel-eluting stent on lowering the risk of restenosis. About other risk factors, e.g. age, sex, smoking, hypertension, the results of trials had inconsistent. |
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