杏香兔耳风洗液对家兔皮肤和阴道黏膜刺激性的实验研究

目的：观察杏香兔耳风洗液对家兔皮肤和阴道黏膜的刺激反应，为其生产和临床安全用药提供参考依据。方法按照《消毒技术规范》（2002年版）进行急性皮肤刺激试验和多次阴道黏膜刺激性试验，并进行安全性评价。结果实验兔皮肤刺激反应积分为0；受试物4种稀释度的多次阴道黏膜刺激反应积分为1.45、0.67、0.11、0.11。结论该洗液对实验兔皮肤无刺激，对实验兔阴道黏膜刺激反应强度为极轻刺激。

Experimental observation on skin and vaginal mucosa irritation of Ainsliaea fragrans Champ Lotion on rabbits

Objective To observe the irritant reaction of skin and vaginal mucosa on rabbits caused by the Ainsliaea fragrans Champ lotion,To provide theoretical evidence for production and clinical safe medication. Methods The acute dermal irritation test and vaginal mucosa sequential irritation test were carried out,and to make safety assessment according to the Technical Stan-dard For Disinfection（2002）. Results The dermal irritation index was zero,vaginal mucosa irritation index of the four dilutions was 1.45,0.67,0.11,0.11. Conclusion This lotion has no dermal irritation and has very light irritation on rabbits’vaginal mucosa.