| 蒙药甘露益肝滴丸提取工艺研究 |
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| 引用本文： | 包桂花,巴根那,白明纲,哈斯,康廷国.蒙药甘露益肝滴丸提取工艺研究[J].中国民族医药杂志,2008,14(11):58-59. |
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| 作者姓名： | 包桂花 巴根那 白明纲 哈斯 康廷国 |
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| 作者单位： | 1. 内蒙古民族大学,通辽,028000
2. 辽宁中医药大学,沈阳,110082 |
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| 摘 要： | 目的：为蒙药甘露益肝滴丸优化乙醇渗漉提取工艺条件。方法：采用L9（34）正交表设计试验,HPLC法测定评价指标胡椒碱的提取转移率,同时考察总浸出物,结果进行方差分析。结果：最佳工艺条件为A1B2C1方案,主要影响因素依次为乙醇浓度（A,P〈0.01）、渗漉速度（C,P〈0.01）、乙醇用量（B,P〈0.05）。结论：制备蒙药甘露益肝滴丸,乙醇渗漉提取荜茇等药材的最佳工艺参数为,取药物粗粉,要用8倍量（B2）的90%乙醇（A1）、以1ml/min的速度（C1）依法缓缓渗漉。胡椒碱的转移率可达99%。
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| 关 键 词： | 甘露益肝滴丸 胡椒碱 渗漉法 提取工艺 正交设计 |
Technology research on Mongolia traditional medical with Mannan nourshing liver pill |
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| BAO Gui-hua,KANG Ting-guo,BA Gen-nal,BAI Ming-gang,HA Si.Technology research on Mongolia traditional medical with Mannan nourshing liver pill[J].Journal of Medicine & Pharmacy of Chinese Minorities,2008,14(11):58-59. |
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| Authors: | BAO Gui-hua KANG Ting-guo BA Gen-nal BAI Ming-gang HA Si |
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| Institution: | BAO Gui - hua, KANG Ting - guo, BA Gen -na, BAI Ming - gang, HA Si(1. College of Mongolian Medicine and pharmacology, Inner Mongolia University for the Nationalities (Tongliao, 028000 ); 2. Liaoning University of Traditional Chinese Medicine, Shenyang 110032) |
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| Abstract: | Objective: To Mongolian medicine Ganluyigan dropping pills Optimization percolation method the extraction process.Method: L9(34) orthogonal design of experiments,HPLC method of evaluation index piperine transfer rate of extraction,leaching of the total inspection at the same time,the results of analysis of variance.Results: The best of conditions is A1B2C1 programme,main factors were alcohol concentration(A,P<0.01),percolation Speed(C,P<0.01),alcohol consumption(B,P<0.05).Conclusion: Prepares Ganluyigan dropping pills,alcohol percolatio method extraction Bibo and other ingredients from the best technical parameters for,to use eight times the amount(B2) of 90% alcohol(A1),Must be 1ml/min speed(C1) in accordance with the law slowly percolation.piperine the transfer rate of up to 99%. |
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| Keywords: | Ganluyigan dropping pills piperine percolation method extraction process orthogonal design |
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