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Comparsion analysis of data mining models applied to clinical research in Traditional Chinese Medicine
Institution:1. Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China;2. Key Laboratory of Advanced Information Science and Network Technology of Beijing, Beijing Jiaotong University, Beijing 100044, China;3. Academic Department, China Academy of Chinese Medical Sciences, Beijing 100700, China;4. Scientific Research Department, China Academy of Chinese Medical Sciences, Beijing 100700, China;5. Personnel Department, China Academy of Chinese Medical Sciences, Beijing 100700, China;6. Executive Vice President, China Academy of Chinese Medical Sciences, Beijing 100700, China;7. Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China;8. Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China
Abstract:ObjectiveTo help researchers selecting appropriate data mining models to provide better evidence for the clinical practice of Traditional Chinese Medicine (TCM) diagnosis and therapy.MethodsClinical issues based on data mining models were comprehensively summarized from four significant elements of the clinical studies: symptoms, symptom patterns, herbs, and efficacy. Existing problems were further generalized to determine the relevant factors of the performance of data mining models, e.g. data type, samples, parameters, variable labels. Combining these relevant factors, the TCM clinical data features were compared with regards to statistical characters and informatics properties. Data models were compared simultaneously from the view of applied conditions and suitable scopes.ResultsThe main application problems were the inconsistent data type and the small samples for the used data mining models, which caused the inappropriate results, even the mistake results. These features, i.e. advantages, disadvantages, satisfied data types, tasks of data mining, and the TCM issues, were summarized and compared.ConclusionBy aiming at the special features of different data mining models, the clinical doctors could select the suitable data mining models to resolve the TCM problem.
Keywords:Medicine  Chinese traditional  Biomedical research  Data mining  Model  Comparison analysis
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