| 高尔基体糖蛋白-73异常表达与肝癌诊断 |
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| 引用本文： | 赛文莉,姚登福. 高尔基体糖蛋白-73异常表达与肝癌诊断[J]. 胃肠病学和肝病学杂志, 2011, 20(1): 8-10 |
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| 作者姓名： | 赛文莉 姚登福 |
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| 作者单位： | 南通大学附属医院临床医学研究中心,江苏,南通,226001 |
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| 基金项目： | 南通市社会发展项目(S2009038); 南通大学附属医院项目(TDFY09003) |
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| 摘 要： | 高尔基体糖蛋白-73（GP73）为经糖基化修饰的膜蛋白,肝癌患者中GP73上调表达。外周血中较高水平的GP73与肝癌相关,在肝癌早期诊断方面,GP73优于AFP,是一具有较高临床诊断价值的新的肝癌标志物。
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| 关 键 词： | 肝细胞癌 高尔基体糖蛋白-73 诊断 |
Abnormal expression of golgi glycoprotein 73 and diagnosis of hepatocellular carcinoma |
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| SAI Wenli,YAO Dengfu. Abnormal expression of golgi glycoprotein 73 and diagnosis of hepatocellular carcinoma[J]. Chinese Journal of Gastroenterology and Hepatology, 2011, 20(1): 8-10 |
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| Authors: | SAI Wenli YAO Dengfu |
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| Affiliation: | SAI Wenli,YAO Dengfu Research Center of Clinical Medicine,the Affiliated Hospital of Nantong University,Nantong 226001,China |
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| Abstract: | Golgi glycoprotein-73(GP73) is a fucosylated glycosylation and up-regulated in hepatocellular carcinoma(HCC).Higher levels of GP73 can be found in the serum of patients with HCC.GP73 could be better than AFP for the diagnosis of early HCC and should be a new tumor marker for HCC diagnosis. |
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| Keywords: | Hepatocellular carcinoma Golgi glycoprotein 73 Diagnosis |
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