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急性空肠弯曲菌肠炎的临床特征及耐药性分析
引用本文:陈杰,孙新婷,曾争,王贵强,于岩岩. 急性空肠弯曲菌肠炎的临床特征及耐药性分析[J]. 传染病信息, 2011, 24(1): 21-22,25
作者姓名:陈杰  孙新婷  曾争  王贵强  于岩岩
作者单位:北京大学第一医院感染性疾病科,100034
摘    要:
目的分析急性空肠弯曲菌肠炎的临床特征及耐药性特点,为北京地区该病流行病学的研究、临床诊断及合理用药提供依据。方法回顾性分析2005--2009年夏秋季我院142例急性空肠弯曲菌肠炎患者的临床特点,应用Kirby—Bauer纸片扩散法行药敏检查。结果6月为发病高峰,发病者以20~29岁最多(49例),临床表现为腹泻,以稀水样或黏液样便为主(138例,97.2%),脓血便或黏液脓血便少见。腹痛103例(72.5%)、发热92例(64.8%)、恶心30例(21.1%)、里急后重26例(18.3%)、呕吐15例(10.6%)。对60例分离的空肠弯曲菌菌株行耐药检测,其中红霉素耐药4株(6.7%)、庆大霉素耐药7株(11.7%)、阿奇霉素耐药1株(1.7%)、头孢派酮耐药60株(100.0%)、左氧氟沙星耐药36株(60.0%)。无死亡病例和并发吉兰-巴雷综合征及反应性关节炎者。结论急性空肠弯曲菌肠炎临床表现及耐药状况呈多样化和复杂化,绝大多数患者表现为良性临床经过。患者对头孢类抗生素敏感程度低,红霉素类可考虑作为抗菌治疗的首选抗生素之一。

关 键 词:空肠弯曲杆菌  抗药性  体征和症状

Clinical features and drug resistance in patients with acute Campylobacter jejuni-induced enteritis
CHEN Jie,SUN Xin-ting,ZENG Zheng,WANG Gui-qiang,YU Yan-yan. Clinical features and drug resistance in patients with acute Campylobacter jejuni-induced enteritis[J]. Infectious Disease Information, 2011, 24(1): 21-22,25
Authors:CHEN Jie  SUN Xin-ting  ZENG Zheng  WANG Gui-qiang  YU Yan-yan
Affiliation:CHEN Jie,SUN Xin-ting,ZENG Zheng,WANG Gui-qiang,YU Yan-yan Department of Infectious Diseases,Peking University First Hospital,Beijing 100034,China
Abstract:
Objective To investigate clinical features and drug resistance in patients with acute Campylobacter jejuni-induced enteritis and to provide evidence for epidemiological study,clinical diagnosis and rational drug use of the disease in Beijing.Methods Clinical features were analyzed retrospectively in 142 patients with acute Campylobacter jejuni-induced enteritis treated in our hospital in the summer or autumn from 2005 to 2009.Antimicrobial susceptibility testing was performed by Kirby-Bauer disk diffusion m...
Keywords:Campylobacter jejuni  drug resistance  signs and symptoms  
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