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| 失交感神经支配对大鼠下颌骨牵张成骨影响的研究 | |
| 引用本文： | 王涛,雷德林,王磊,曹健,张雅博,杜兆杰. 失交感神经支配对大鼠下颌骨牵张成骨影响的研究[J]. 创伤外科杂志, 2011, 13(1): 54-58 |
| 作者姓名： | 王涛 雷德林 王磊 曹健 张雅博 杜兆杰 |
| 作者单位： | 西安,第四军医大学口腔医学院口腔颌面外科,陕西,710032 |
| 摘 要： | 目的探讨失交感神经支配对大鼠下颌骨牵张成骨新骨形成的影响。方法雄性SD大鼠30只,随机分为2组,对照组（A组,15只）实施右侧下颌骨牵张成骨,实验组（B组,15只）实施双侧颈交感干离断及右侧下颌骨牵张成骨。术后在固定期1、14、28天取材,对牵张间隙新生骨痂进行大体形态及HE染色骨组织定量观察。应用SPSS12.0软件包进行两样本t检验。结果两组牵张间隙均充满新生骨痂,在固定期1、14天实验组比对照组新生骨痂更平整连续,在固定期28天两组未见明显差异;石蜡切片HE染色显示实验组较对照组有更多新骨形成,在固定期1、14及28天时,牵张间隙实验组的骨量百分比均高于对照组（P〈0.05）。结论失交感神经支配可增强下颌骨牵张成骨新骨形成,提示交感神经系统在牵张成骨过程中起到一定调控作用。 |
| 关 键 词： | 牵张成骨 交感神经 下颌骨 大鼠 |
Effects of sympathetic innervation loss on rat mandibular distraction osteogenesis |
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| WANG Tao,LEI De-lin,WANG Lei,et al.. Effects of sympathetic innervation loss on rat mandibular distraction osteogenesis[J]. Journal of Traumatic Surgery, 2011, 13(1): 54-58 | |
| Authors: | WANG Tao LEI De-lin WANG Lei et al. |
| Affiliation: | WANG Tao,LEI De-lin,WANG Lei,et al.(Department of Oral and Maxillofacial Surgery,Stomatological Hospital,Fourth Military Medical University,Shanxi 710032,China) |
| Abstract: | Objective To investigate the effects of sympathetic innervation loss on new bone formation in rat mandibular distraction osteogenesis.Methods A total of 30 male Sprague-Dawley rats were divided into two groups randomly.Control group(group A,n=15) only underwent right mandibular distraction osteogenesis,and experimental group(group B,n=15) underwent bilateral transection of cervical sympathetic trunk(TCST) and then right mandibular distraction osteogenesis.The rats were sacrificed at consolidation time of 1,... |
| Keywords: | distraction osteogenesis sympathetic nerve mandible rats |
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