| Xp11.2易位性肾癌的研究进展 |
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| 引用本文： | Huang JH,Zhou FJ. Xp11.2易位性肾癌的研究进展[J]. 癌症, 2008, 27(9): 1006-1008 |
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| 作者姓名： | Huang JH Zhou FJ |
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| 作者单位： | 华南肿瘤学国家重点实验室,广东广州,510060;中山大学肿瘤防治中心泌尿外科,广东广州,510060;华南肿瘤学国家重点实验室,广东广州,510060;中山大学肿瘤防治中心泌尿外科,广东广州,510060 |
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| 摘 要： | Xp11.2易位性肾癌是2004年WHO肾细胞癌病理组织学分类中新增的类型.虽然其总体发病率很低,但在儿童肾癌患者中约1/3为此类肾癌.它的临床表现、病理组织学特点、生物学行为及预后都有别于其它类型的肾癌.目前关于Xp11.2易位性肾癌的报道少见.本文对近年来有关Xp11.2易位性肾癌的研究作一综述,分别对其分型、流行病学特点、临床及病理组织学特点、诊断、治疗及预后等方面进行初步总结.
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| 关 键 词： | 肾肿瘤 Xp11.2易位 融合基因 分型 诊断 治疗 |
Research advances in Xp11.2 translocation renal cell carcinoma |
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| Huang Jian-Hua,Zhou Fang-Jian. Research advances in Xp11.2 translocation renal cell carcinoma[J]. Chinese journal of cancer, 2008, 27(9): 1006-1008 |
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| Authors: | Huang Jian-Hua Zhou Fang-Jian |
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| Affiliation: | State Key Laboratory of Oncology in South China, Guangzhou, Guangdong, 510060, PR China. |
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| Abstract: | Xp11.2 translocation renal cell carcinoma(RCC) is a newly identified category of RCC described in the 2004 WHO Classification of Kidney Tumors.Although the incidence is very rare,it accounts about one third of pediatric RCCs.It is different from other RCCs in clinical manifestations,histopathologic features,biological behaviour and prognosis.At present,Xp11.2 translocation RCC has seldom been reported.This review analyzed recent researches on Xp11.2 translocation RCC,described its classification and summarized the characteristics of epidemiology,clinical manifestations,histopathology,diagnosis,treatment and prognosis. |
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| Keywords: | Renal neoplasm Xp11.2 translocation Fusion gene Classification Diagnosis Therapy |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ |
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