九牛造化学成分研究

目的:研究九牛造根中的化学成分。方法:采用硅胶柱层析和葡聚糖凝胶柱层析分离纯化技术,通过理化性质和波谱特征分离并鉴定化合物。结果:从九牛造根的丙酮提取物中分离鉴定出8个化合物,分别为大戟甾醇(eupholⅠ)、5-羟甲基糠醛(5-hydroxymethylfuraldehydeⅡ)、β-谷甾醇(β-sitosterolⅢ)、β-胡萝卜苷(β-sitosterolglucosideⅣ)、3,3′,4-三甲基鞣花酸(3,3′,4-tri-o-methylellagic acidⅤ)、3,3′-二甲基鞣花酸(3,3′-di-methylellagicacidⅥ)、3,3′-二甲基鞣花酸-4′-β-D-木糖苷(3,3′-di-methylellagic acid-4′-o-β-dxylopyranosidⅦ)、没食子酸(gallicacidⅧ)。结论:所分离得到的化合物Ⅱ、Ⅵ、Ⅶ、Ⅷ为首次从该植物中分离得到。

Study on Chemical Constituents of Euphorbia hylonoma Hand.-Mazz.

OBJECTIVE: To study the constituents of the roots of Euphorbia hylonoma Hand. -Mazz. METHODS: The chemical constituents were isolated and purified by solvent extraction together with various chromatographic techniques, the structures were elucidated on the basis of chemical properties and spectral data. RESULTS: Eight compounds were isolated from the acetone extracts of the roots of Euphorbia hylonoma Hand-Mazz., which were euphol(I), 5-hydroxymethylfuraldehyde(II), beta-sitosterol(III), beta-sitosterol glucoside (IV),3,3',4-tri-o-methylellagic acid(V), 3, 3' tdi-o-methylellagic acid (VI),3,3'-di-o-methylellagic acid-4'-o-beta-dxylopyranosid (VII), gallic acid(VIII). CONCLUSION: The compounds II, VI, VII, VIII were isolated from Euphorbia hylonoma Hand-Mazz. for the first time.