精索静脉高位结扎术对抗精子抗体、精子顶体酶活性及精子数量、活动力的影响

目的探讨精索静脉曲张患者在精索静脉高位结扎术前、后精液中抗精子抗体、精子顶体酶活性及精子数量、活动力的变化。方法选取精索静脉曲张患者35例。用混合抗球蛋白凝集法(MAR)、改良的Kennedy法测定术前和术后3～6个月精液中抗精子抗体、精子顶体酶活性及精子计数、活动力(a及b级活动力精子的百分率)测定。结果精索静脉高位结扎术后患者精液中抗精子抗体有下降、精子顶体酶活性较术前明显增高、精子数量增加、活动力升高。结论精索静脉高位结扎术对精索静脉曲张患者精液中抗精子抗体的下降、精子顶体酶活性的提高、精液质量的提高有帮助。

THE EFFECT OF VARICOCELE LIGATION ON ANTISPERM ANTIBODY AND ACROSIN ACTIVITY

Objective To study the effect of antisperm antibody and acrosin activity before and after high ligation of spermatic vein for patient with varicocele. Methods 35 infertile men who have visible varicocele. The modified Kenedy s method was used to determine sperm acmsin activity, seminal fuild assay and ASAB were exam- ined. Results sperm acmsin activity was increased significantly, antisperm antibody was also come down. Sperm con- centration,sperm motility were remarkably improved. Conclusion In the patients with varicocele the semen quality and quantity can be improved obviously, sperm acrosin activity was increased significantly, antisperm antibody was come down after high ligation of spermatic vein.