肺癌患者并发静脉血栓与肺栓塞的危险因素分析简

目的 探讨肺癌患者并发静脉血栓或肺栓塞的高危因素.方法 分析我院收治的35例肺癌合并静脉血栓栓塞患者资料,选择同期未发生静脉血栓的病例资料做对照,探求肺癌并发静脉血栓或肺栓塞的危险因素.结果 （1）静脉血栓发生时间构成以确诊后3个月内比重最高,占31.4%;静脉血栓发生部位以左下肢深静脉血栓为主,占40.0%.（2）腺癌、高病理分级、D-二聚体升高是肺癌合并静脉血栓或肺栓塞的独立危险因素,各因素的OR值分别为7.207、3.480、2.863.结论 肺癌诊断3个月内是并发静脉血栓栓塞的高发时段;肿瘤分级高、腺癌、D-二聚体水平升高的肺癌患者易发生静脉血栓栓塞,临床应对上述因素高度警惕,及早进行预见性治疗.

Analysis on risk factors of lung cancer patients complicated with venous thrombosis and pulmonary embolism

Objective To discuss the high risk factors of lung cancer patients complicated with venous thrombosis or pulmonary embolism. Methods The clinical data of 35 lung cancer patients complicated with venous thromboembolism were compared with another 35 lung cancer patients without venous thromboembolism during the same period. Single factor analysis and logistic regression analysis were introduced to pursuit the risk factors for lung cancer patients with venous thrombosis or pulmonary embolism. Results The incidence of venous thrombosis （31.4%） was the highest during 3 months after confirmed diagnosis. Venous thrombosis occurred mainly in left low er extremity deep vein, accounting for 40%. Adenoearcinoma, high pathological grade, and D-dimer increase were independent risk factors for lung cancer patients with venous thrombosis or pulmonary embolism. Conclusion 3 months after confirmed diagnosis is the peak time for occurrence of venous thromboembolism and pulmonary embol ism. The independent risk factors include adenocareinoma, high pathological grade, and D-dimer increase, which should be paid more attention and given early prevention.