强脉冲光联合调Q激光治疗色素增生性皮肤病

目的探讨强脉冲光联合调Q激光疗法对面部色素增生性皮肤病的疗效及安全性。方法根据患者面部色素性疾病的特点，对225例FitzpatrickⅢ、Ⅳ型皮肤的色素细胞增生性皮肤病患者，采用560nm强脉冲光联合调Q532nm激光治疗，首先使用560nm强脉冲光，能量密度30～40J／cm2的光子嫩肤治疗，每月1次，3个月后观察疗效。对于改善不品著的脂溢性角化斑、咖啡斑及眼睑、口唇周围残留的雀斑等，再使用调Q532nm激光，施行局部针对性治疗，能量密度70J／cm2。于激光治疗后2个月，对皮损的改善和满意度进行评估并记录不良反应。结果90％患者的雀斑、咖啡斑、脂溢性角化斑的色素均有50％～70％不同程度的消退，同时毛细血管扩张、毛孔粗大、细小皱纹均达到了60％以上的程度的改善。主要并发症为暂时性红斑和水疱。结论560nm强脉冲光联合调Q激光治疗面部色素增生性皮肤病安全有效，同时能有效改善肤质。

Non-ablative treatment for hyperpigmented skin diseases with combined intense pulse light and Q switched Nd :YAG laser

Objective To observe the effect of non-ablative treatment combined intense pulse light (IPL) and Q switched Nd :YAG laser on hyperpigmented skin diseases. Methods Total 250 cases of Fitzpatrick skin types Ⅲ and Ⅳ with hyperpigmented skin disorders received 4 treatments with combined 560nm IPI. and 532 nm Q switched Nd :YAG laser. The interval between two treat-ments was I month. After 3 months the effect of IPL was observed. If it was not good, we used the Q switched Nd :YAG laser. Efficacy and adverse effects were evaluated 3-6 months after the final treat-ment. Results 3-6 months after the last treatment, 50%-70% of patients had their telangiectasia, enlarged pores, hyperpigmentation and wrinking of facial photoaging improved. The degree of im-provement was more than 60 %. Common side effects were minor blistering and erythema. Conclusion Combined IPI. and Q switched Nd :YAG laser treatment is an idea non-ablative therapy for telangi-ectasia, enlarged pores, hyperpigmentation and wrinking of facial photoaging in Fitzpatrick skin types Ⅲ and Ⅳ in Asian.