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纳络酮治疗重度新生儿缺氧缺血性脑病的疗效观察
引用本文:胡女元,郭青云,上官明. 纳络酮治疗重度新生儿缺氧缺血性脑病的疗效观察[J]. 国际医药卫生导报, 2005, 11(6): 34-36
作者姓名:胡女元  郭青云  上官明
作者单位:江门市中心医院儿科,广东,江门,529071;江门市中心医院儿科,广东,江门,529071;江门市中心医院儿科,广东,江门,529071
摘    要:目的观察纳络酮治疗重度新生儿缺氧缺血性脑病(HIE)的疗效。方法在常规治疗的基础上对36例重度HIE加用纳络酮治疗,并与常规治疗的24例比较。结果治疗组有效率明显优于对照组(p<0.01)。纳络酮可使患儿临床症状明显好转,明显缩短中枢性呼吸衰竭、循环不良和胃肠功能紊乱消失时间,并提高其存活率。结论纳络酮治疗HIE疗效显著,未见副作用发生。

关 键 词:纳络酮  婴儿  新生  缺氧缺血性脑病
文章编号:1007-1245(2005)06-0034-03
修稿时间:2004-12-13

Clinical Observation of Treating Neonatal Hypoxic Ischemic Encephalopathy with Naloxone
HU Nuyuan,GUO Qingyun,SHANG Guanming. Clinical Observation of Treating Neonatal Hypoxic Ischemic Encephalopathy with Naloxone[J]. International Medicine & Health Guidance News, 2005, 11(6): 34-36
Authors:HU Nuyuan  GUO Qingyun  SHANG Guanming
Affiliation:HU Nuyuan GUO Qingyun SHANG Guanming. Department of pediatrics,Jiangmen Central Hospital,Jiangmen 529071,China
Abstract:Objective To observe the effect of naloxone on HIE. Methods On the routine therapy ,the healing group with thirty-six cases of HIE received therapy on naloxone , and compared with the contrast group on routine therapy. Results The effective rate of the healing group was higher than that of the contrast group (p<0.01). Naloxoane can significantly shorten the time of respiratory failure, circulatory system dysfunction and gastro-intestine function failure , and increase the survival rate . Conclusion The therapy with naloxone on HIE is remarkable ,and it has no side effect.
Keywords:Naloxone Infant Newborn Hypoxic ischemic encephalopathy
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