Correlation of class I DNA Pvu II restriction HLA gene fragments with serologic alleles |
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Authors: | G Lucotte C Coulondre C Salmon |
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Affiliation: | Laboratoire de Génétique Moléculaire du CNTS-Institut, Paris, France. |
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Abstract: | Restriction enzyme site polymorphisms for Pvu II endonuclease are examined in a panel of DNAs isolated from peripheral blood lymphocytes of HLA-typed individuals. 21 polymorphic bands are detected from a total of 39 restriction fragments analyzed, only 9 of them corresponding to common variable morphs. Three polymorph fragments only correlate with known HLA-A and -B serologic alleles. |
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