GSTT1 null genotype frequency in a Turkish population |
| |
| Authors: | Basbug Oke Fahri Akbas Muge Aydin Hakan Berkkan |
| |
| Affiliation: | (1) Department of Biochemistry, Faculty of Pharmacy, University of Istanbul, 34452 Istanbul, Turkey, TR;(2) Department of Genetics, Institute for Experimental Medicine, University of Istanbul, Istanbul, Turkey, TR |
| |
| Abstract: | ![]()
In humans, glutathione-S-transferases (GSTs) are involved in the detoxification of xenobiotics. A deletion polymorphism in the glutathione S-transferase Theta 1 gene (GSTT1 null genotype) is associated with an increased risk of certain forms of cancer. The distribution of this polymorphism in 240 healthy individuals has been examined, using a polymerase chain reaction (PCR)-based method. The GSTT1 null genotype frequency was 20% in a Turkish Population. Received: 18 March 1998 / Accepted: 8 April 1998 |
| |
| Keywords: | Glutathione S-transferases (GSTs) GSTT1 Polymerase chain reaction (PCR) |
| 本文献已被 SpringerLink 等数据库收录！ |
|
