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| 比值光谱法测定氯柳酊中的氯霉素和水杨酸 | |
| 引用本文： | 黄喜茹,杨亚军,冯媛媛. 比值光谱法测定氯柳酊中的氯霉素和水杨酸[J]. 河北医科大学学报, 2006, 27(3): 196-198 |
| 作者姓名： | 黄喜茹 杨亚军 冯媛媛 |
| 作者单位： | 河北医科大学药学院分析化学教研室,河北,石家庄,050017;河北医科大学药学院 |
| 摘 要： | 目的建立氯柳酊中氯霉素和水杨酸的比值光谱测定法.方法选择比值光谱的峰点和交点处(260.0 nm和291.6 nm)作为测定波长,直接测定氯柳酊中二组分的含量.结果氯霉素和水杨酸的平均回收率和相对标准偏差分别为99.67%,0.52%和100.0%,0.66%.结论该方法简便、快速、准确,适用于医院制剂氯柳酊的质量检测. |
| 关 键 词： | 光谱分析 氯霉素 水杨酸 氯柳酊 |
| 文章编号： | 1007-3205(2006)03-0196-03 |
| 收稿时间： | 2005-10-21 |
| 修稿时间： | 2005-11-17 |
DETERMINATION OF CHLORAMPHENICOL AND SALICYLIC ACID IN TINCTURE BY RATIO SPECTROPHOTOMETRY |
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| HUANG Xi-ru,YANG Ya-jun,FENG Yuan-yuan. DETERMINATION OF CHLORAMPHENICOL AND SALICYLIC ACID IN TINCTURE BY RATIO SPECTROPHOTOMETRY[J]. Journal of Hebei Medical University, 2006, 27(3): 196-198 | |
| Authors: | HUANG Xi-ru YANG Ya-jun FENG Yuan-yuan |
| Affiliation: | 1. Department of Analytical Chemistry, the School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang 050017, China ;2. 2001 Grade Graduate, the School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang 050017, China |
| Abstract: | ObjectiveTo establish ratio spectrophotometry for determination of chloramphenicol and salicylic acid in tincture.MethodsThe wavelength pair((260.0) nm and(291.6) nm) were selected at the peak point and intersection point of ratio spectra,to eliminate the interference of other components.ResultsThe average recoveries and relative standard deviations of chloramphenicol and salicylic acid were(99.67 %),(0.52 %) and(100.0 %),(0.66 %),respectively.ConclusionThe method was simple,rapid and accurate,which can be used for determination of chloramphenicol and salicylic acid in tincture. |
| Keywords: | spectrum analysis chloramphenicol salicylic acid tincture |
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