| Abstract: | ![]()
Rats were restrained for 4 h or for 4 h per day on three consecutive days and blood samples were obtained 30 min after their release. The adenosine deaminase (ADA) activity in the serum was measured by a micro-method with quantitation of the ammonia generated by ADA. Repeated restraint stress significantly (p<0·05) elevated serum ADA activity, while a single 4 h episode of restraint stress had no affect on this activity. It seems possible that the increase in ADA activity in the former case might have been related to the enhanced differentiation and maturation of suppressor T cells. To our knowledge, the present results are the first to demonstrate that serum ADA activity can be affected by stress. © 1998 John Wiley & Sons, Ltd. |
