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| 头颈部鳞癌肿瘤间质液压的检测 | |
| 引用本文： | 李蜀光,毛祖彝,徐平平,李思毅. 头颈部鳞癌肿瘤间质液压的检测[J]. 肿瘤学杂志, 1997, 0(1) |
| 作者姓名： | 李蜀光 毛祖彝 徐平平 李思毅 |
| 作者单位： | 华西医科大学口腔医学院!成都，610041，华西医科大学口腔医学院!成都，610041，华西医科大学口腔医学院!成都，610041，华西医科大学口腔医学院!成都，610041 |
| 摘 要： | 目的：为了检测头颈部鳞癌病人的肿瘤间质液压（TIFP）。方法：采用国产ZYH－3型组织液压测量仪，检测了16例头颈部鳞癌原发灶及4例转移灶的TIFP。结果：发现头颈部鳞癌原发灶和转移灶的TFFP都增高，测得的TIFP值与肿瘤体积具有良好的相关关系。结论：TIFP增高是恶性肿瘤的一项重要病理生理学特征。TIFP增高是抗癌药和免疫因子进入肿瘤的病理学障碍，因此，设法降低TIFP具有重要意义。 |
| 关 键 词： | 头颈部肿瘤 癌.鳞状细胞 肿瘤间质液压 |
Measurement of Tumor Intersititial Fluid Pressure in Squamous Cell Carcinoma of Head and Neck |
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| Li Shuguang, Mao Zuyi, Xu Pingping et al.. Measurement of Tumor Intersititial Fluid Pressure in Squamous Cell Carcinoma of Head and Neck[J]. Journal of Chinese Oncology, 1997, 0(1) | |
| Authors: | Li Shuguang Mao Zuyi Xu Pingping et al. |
| Affiliation: | College of Stomatology. West China University of Medical Science .Chengdu610041 |
| Abstract: | Purpose: To measure the tumor intersititial fluid pressure(TIFP)in patients with squamous cell carcinoma of head andneck. Method: We successfuly measured 16 squamous cell carcinoma lesions and 5 metastasis lesions of head and neck by type ZYH-3 in-tersititial fluid pressure monitor. Results: The results showed that the TIFP was elevated in all lesions. Furthermore, the TIFP in-creased with tumor size. There was a good correlation between TIFP and tumor volume. Conclusion: Elevated TIFP is a pathophysi-ological characteristic of maglinancy. It may be a physiological barrier impacting the distribution of therapeutic drugs, antibodies andother macromoles on cancer detection and treatment. Therefore, it is important to develop strategies to decrease TIFP. |
| Keywords: | Head and neck neoplasms Carcinoma squamous cell Tumor intersititial fluid pressure |
| 本文献已被 CNKI 等数据库收录！ | |