冠心病与牙周病及相关危险因素的多因素Logistic回归分析

目的探讨牙周病与冠心病发生的关系。方法采用病例对照研究，病例组为冠心病患者162例，对照组为同期非冠心病住院患者162例。对研究对象进行问卷调查和临床专科检查并作详细记录，使用SAS8．1统计学软件对收集的资料进行Logistic回归分析。结果牙周病（95％CI为1．651～4．082，OR=1．164）、工作压力（95％CI为1．920—5．069，OR=3．119）、体质量指数（95％CI为2．298—5．133，OR=3．434）、心血管病家族史（95％CI为1．616～5．410，OR=2．957）、高血压（95％CI为2．061～6．455，OR=3．647）、高脂饮食（95％CI为1．074～2．826，OR=1．659）是冠心病的危险因素（P〈0．05或P〈0．001）。结论应积极预防和治疗牙周病，消除其对冠心病的影响。

Periodontal disease was an independent risk factor of coronary heart disease by multi-factors Logistic regression analysis

Objective To analyze the relationship between periodontal diseases and coronary heart disease （CHD）. Methods One hundred and sixty-two patients were enrolled into ease group and another 162 patients were enrolled into control group. Subjects were underwent questionaire investigation and clinic examination. Statistic analysis was performed using multi-factors Logistic regression analysis. Results periodontal diseases （ 95% CI 1. 651 - 4. 082, OR = 1. 164 ） , working stress （ 95% CI 1. 920 - 5.069, OR = 3. 119） ,obesity （ 95% CI 2. 298 - 5. 133, OR = 3.434 ）, family history of cardiovascular diseases （ 95% CI 1.616 - 5.410, OR = 2. 957 ）, hypertension （ 95 % CI 2. 061 - 6. 455, OR = 3. 647 ） and fat-enriched diet （ 95 % CI 1. 074 - 2. 826, OR = 1. 659） were independent risk factors for CHD （ P 〈 0. 05 or P 〈 0. 001 ）. Conclusion Dentist can help to prevent coronary heart diseases by preventing and curing the periodontal diseases.