首页 | 本学科首页   官方微博 | 高级检索  
     


Ziprasidone suppresses olanzapine-induced increases in ingestive behaviour in the rat
Authors:Kirk Shona L  Neill Joanna C  Jones Declan N C  Reynolds Gavin P
Affiliation:Bradford School of Pharmacy, University of Bradford, Bradford BD7 1DP, UK.
Abstract:
Many atypical antipsychotic drugs, such as olanzapine, induce significant weight gain. However, ziprasidone produces minimal weight gain, the mechanism of which remains unclear. The aim of the present study was to investigate whether ziprasidone would reduce the acute effect of olanzapine on feeding behaviour. The results suggest that ziprasidone suppresses the significant increases in food intake produced by olanzapine, indicating that it has an intrinsic protective mechanism against drug-induced increases in food intake.
Keywords:
本文献已被 PubMed 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号