Seventeen more novel HLA-A locus alleles |
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| Authors: | Ellis J Steiner N Kosman C Henson V Mitton W Koester R Ng J Hartzman R J Hurley C K |
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| Affiliation: | Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, USA. |
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| Abstract: | ![]()
This paper describes seventeen novel HLA-A locus alleles: A*0106, *0235, *0236, *0237, *1105, *2302, *2303, *24032, *2422, *2424, *2503, *2613, *3007, *3203, *3204, *6809 and *6810. All alleles were identified due to unexpected probe reaction patterns during routine SSOP typing. Exons 2 and 3 of these alleles were subsequently characterized by DNA sequencing. The alleles represent a shuffling of sequence motifs, likely by interallelic conversion, expanding the diversity of the HLA system. |
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| Keywords: | SSOP DNA sequencing HLA-A locus |
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