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| 乙型/丙型肝炎病毒相关性肝细胞癌450例分析 | |
| 引用本文： | 谭炳芹,王昌源,杜磊,张立华,董格峰. 乙型/丙型肝炎病毒相关性肝细胞癌450例分析[J]. 中国病原生物学杂志, 2010, 0(4) |
| 作者姓名： | 谭炳芹 王昌源 杜磊 张立华 董格峰 |
| 作者单位： | 山东大学医学院济南市传染病医院; |
| 基金项目： | 济南市科技局资助项目(济科合200807033-1) |
| 摘 要： | 目的比较乙型/丙型肝炎病毒(HBV/HCV)相关性肝细胞癌(HCC)的特点,探讨HCC发生的相关因素。方法收集2005年1月～2009年7月济南市传染病医院450例确诊的HCC住院患者病史及血清学资料,建立数据库,应用SPSS16.0软件进行统计分析。结果450例HCC患者HBV、HCV、HBV合并HCV感染分别为422、17例和11例。422例HBV感染者平均年龄(53.85±10.00)岁,高发年龄为50～59岁,男女比例为7.79∶1;17例HCV感染者平均年龄(60.18±5.47)岁,高发年龄为60～69岁,男女比例为2.40∶1。HCV相关性HCC(C-HCC)患者的发病年龄高于HBV相关性HCC(B-HCC)患者;B-HCC男性患者比例高于C-HCC;高病毒载量及长期肝炎发作是HCC形成的相关因素;C-HCC患者中2型糖尿病比例高于B-HCC患者。结论HBV感染所致的肝炎较HCV所致的肝炎更容易发生HCC。年龄大、男性、肝炎史长、肝硬化是HBV/HCV相关性HCC的主要相关因素。 |
| 关 键 词： | 肝炎病毒 乙型 丙型 肝细胞癌 相关因素 |
Analysis of 450 patients with hepatocellular carcinoma associated with hepatitis B virus and/or hepatitis C virus |
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| TAN Bing-qin,WANG Chang-yuan,DU Lei,ZHANG Li-hua,DONG Ge-feng. Analysis of 450 patients with hepatocellular carcinoma associated with hepatitis B virus and/or hepatitis C virus[J]. Journal of Pathogen Biology, 2010, 0(4) | |
| Authors: | TAN Bing-qin WANG Chang-yuan DU Lei ZHANG Li-hua DONG Ge-feng |
| Affiliation: | TAN Bing-qin,WANG Chang-yuan,DU Lei,ZHANG Li-hua,DONG Ge-feng(Jinan Infectious Disease Hospital,Sh,ong University,Jinan 250021,China) |
| Abstract: | Objective To compare the characteristics of hepatitis-B-virus-related hepatocellular carcinoma(B-HCC)with hepatitis-C-virus-related hepatocellular carcinoma(C-HCC)and to explore factors related to the development of hepatocellular carcinoma(HCC).Methods Records of patients hospitalized for HCC from January 2005 to July 2009 were reviewed.Case histories and serology information were collected,and a database was established and analyzed with SPSS16.0 software.Results Of 450 patients with HCC,422 had B-HCC,17 ... |
| Keywords: | Hepatitis B virus hepatitis C virus hepatocellular carcinoma related factors |
| 本文献已被 CNKI 等数据库收录！ | |