氩氦刀冷冻治疗颅内肿瘤12例

目的 探讨氩氦刀在颅内肿瘤治疗中的应用效果。方法 在12例较大的颅内肿瘤(胶质母细胞瘤7例,脑膜瘤3例,星形细胞瘤2例,最大径为5.5～12cm。)的治疗中,依肿瘤大小选择合适的冷冻刀进行冷冻,在20s内达到-140℃左右,维持5min后快速复温达37℃。如此冷冻-复温重复进行2～3次。然后按冷冻范围切除肿瘤。术后常规放、化疗,并予跟踪随访。结果 肿瘤全切11例,大部切除1例,术中出血极少。3例胶质母细胞瘤和1例垦形细胞瘤分别于术后第7个月(2例)、9个月、12个月复发,其中2例已死亡。其余8例已随访11～13个月,尚无复发迹象。结论 在颅内肿瘤切除术中应用氩氦刀进行冷冻处置,可以极大减少术中出血,降低手术风险,延缓恶性肿瘤的复发。但其远期疗效尚有待观察。

Cryosurgery of 12 Cases Intracranial Tumors with Cryocare Surgical System

Objective To investigate the effect of treating intracranial tumors with cryocare surgical system. Methods We used cryocare surgical system to treat 12 cases large intracranial tumors by freezing, re-warming, re-freezing, and then remove them by operation. Results 11 cases inbacianial tumors were removed totally by cryocare surgical system with less hemorrhage, 4 cases gli-oma recurred at the 7th -month(2 cases) ,the 9th- month ,and the 12th-month after operation, two of them died. Conclusion Cryocare surgical system is able to remove intracranial tumors with little hemorrhage and danger , and delay the recurrence of malignant tumors, but its long term effects still need to be observed further.