肥胖类型与脑卒中亚型的相关性研究

目的探讨肥胖类型与脑卒中亚型的相关性。方法将573例急性脑卒中患者分为脑出血组126例,脑梗死组447例,脑梗死组再分为脑血栓形成组(215例)和腔隙性脑梗死组(232例),另外选择277例无脑卒中者为对照组。测量腰围、臀围和体重,计算体重指数和腰臀比(WHR),分析肥胖参数与脑卒中各亚组的关系。结果脑卒中各亚组与对照组肥胖发生率差异无显著性意义(P>0.05);各组WHR明显大于对照组(P<0.05)。WHR增大明显增加脑卒中各亚组的危险性(P<0.05);女性腹围增大患腔隙性脑梗死危险性升高(P<0.05);男性体重增加患脑出血的危险性升高(P<0.01)。结论腹型肥胖是脑出血、脑血栓形成和腔隙性脑梗死的危险因素之一。

Study on correlation between types of obesity and subtypes of stroke

Objective To investigate the relationship between types of obesity and stroke subtypes.Methods Waist circumference,hip circumference and body mass of 573 patients with acute cerebral accident and 277 controls without stroke were measured.Body mass index(BMI) and waist-to-hip ratio(WHR) were calculated.Relationship between these data and stroke subtypes including brain hemorrhage,cerebral thrombosis and lacunar infarction was analyzed.Results The rate of obesity between patients and controls showed no significant difference(P>0.05).WHR of male and female patients with stroke subtypes was significantly larger than that of controls(P< 0.05).The logistic regression analysis showed that WHR was associated with high risk for all subtypes of stroke(P<0.05).With increasing waist circumference in female patients,the risk of lacunar infarction was enhanced(P<0.05).Body mass of male patients was associated with the risk of intracerebral hemorrhage(P<0.01).Conclusion Abdominal obesity is one of the risk factors for intracerebral hemorrhage,cerebral thrombosis and lacunar infarction.