| 基因治疗非创伤性股骨头坏死的研究进展 |
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| 引用本文： | 周明旺,李盛华,郭铁峰. 基因治疗非创伤性股骨头坏死的研究进展[J]. 中国骨伤, 2012, 25(6): 525-529 |
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| 作者姓名： | 周明旺 李盛华 郭铁峰 |
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| 作者单位： | 甘肃省中医院,甘肃 兰州 730050;天津中医药大学;甘肃省中医院,甘肃 兰州 730050;甘肃中医学院 |
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| 基金项目： | 国家自然科学基金(面向项目)(编号:81072821)Fund programs:Supported by a Grant from National Natural Science Foundation of China (Greneral Program)(No.81072821) |
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| 摘 要： | 非创伤性股骨头坏死早期保守治疗方法甚多,但尚缺乏一种成熟有效的治疗方法。基因治疗非创伤性股骨头坏死是近年来新型的治疗方法,本文就该病的发病机制、分子生物学基础、外源性治疗基因与载体选择等方面研究的相关进展及存在问题展开综述,讨论了研究的有关问题及对策,并就研究前景进行了展望。
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| 关 键 词： | 股骨头坏死 治疗 基因 综述文献 |
| 收稿时间： | 2011-11-22 |
Research progress of gene therapy in the treatment of non-traumatic osteonecrosis of femoral head |
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| ZHOU Ming-wang,LI Sheng-hua and GUO Tie-feng. Research progress of gene therapy in the treatment of non-traumatic osteonecrosis of femoral head[J]. China journal of orthopaedics and traumatology, 2012, 25(6): 525-529 |
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| Authors: | ZHOU Ming-wang LI Sheng-hua GUO Tie-feng |
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| Affiliation: | Gansu Hospital of Traditional Chinese Medicine,Lanzhou 730050,Gansu,China |
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| Abstract: | ABSTRACT There are many methods of conservative treatment for early non-traumatic osteonecrosis of femoral head,but still lack of a mature and effective treatment. Gene therapy is a new treatment method for non-traumatic osteonecrosis of femoral head in recent years. This article showed that the non-traumatic osteonecrosis of femoral head related to progress and problems on pathogenesy,molecular biology foundation,exogenous theoretical gene,carrier selection and so on,discussed some problems and countermeasure and future applications. |
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| Keywords: | Femur head necrosis Therapy Genes Review literature |
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