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PRELIMINARY APPLICATION OF WHOLE BODY DIFFUSION WEIGHTED IMAGING IN SCREENING METASTASIS
作者单位:Yong-jing Guan,Hua-wei Ling,and Ke-min Chen Department of Radiology,Ruijin Hospital,School of Medicine,Shanghai Jiaotong University,Shanghai 200025
摘    要:Objective To investigate the feasibility of whole body diffusion weighted imaging (WB-DWI) in screening metastasis.
Methods WB-DWI was performed in 24 patients diagnosed with various types of primary tumors. The three-dimensional maximum intensity projection reconstruction and black-and-white flip technique were used to observe metastatic lesions, and the results were compared with those of bone scintigraphy.
Results By WB-DWI scanning sequence at b = 800 s/mm^2, all the bone lesions found by bone scintigraphy in the cohort were well identified, and other lesions of soft tissue and organs were also well demonstrated. Its screening capability was equivalent with bone scintigraphy in screening metastases in bones (P = 0.062).
Conclusion WB-DWI was practicable with the parameter settings attempted in metastases screening.

关 键 词:扩散技术  磁共振成像  扩散加权成像  肿瘤转移

PRELIMINARY APPLICATION OF WHOLE BODY DIFFUSION WEIGHTED IMAGING IN SCREENING METASTASIS
Authors:Yong-jing Guan  Hua-wei Ling  Ke-min Chen
Institution:Department of Radiology, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200025
Abstract:Objective To investigate the feasibility of whole body diffusion weighted imaging (WB-DWI) in screening metastasis. Methods WB-DWI was performed in 24 patients diagnosed with various types of primary tumors. The three-dimensional maximum intensity projection reconstruction and black-and-white flip technique were used to observe metastatic lesions, and the results were compared with those of bone scintigraphy. Results By WB-DWI scanning sequence at b = 800 s/mm2, all the bone lesions found by bone scintigraphy in the cohort were well identified, and other lesions of soft tissue and organs were also well demonstrated. Its screening capability was equivalent with bone scintigraphy in screening metastases in bones (P = 0.062). Conclusion WB-DWI was practicable with the parameter settings attempted in metastases screening.
Keywords:magnetic resonance imaging  whole body diffusion weighted imaging  apparent diffusion coefficient  metastasis
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