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| E-选择素与心肌缺血再灌注损伤 | |
| 引用本文： | 董村南,刘跃春. E-选择素与心肌缺血再灌注损伤[J]. 心血管病学进展, 2006, 27(5): 637-639 |
| 作者姓名： | 董村南 刘跃春 |
| 作者单位： | 潍坊医学院,山东,潍坊,261042 |
| 摘 要： | E-选择素是血管内皮细胞合成的一种糖蛋白分子,介导白细胞与内皮细胞的黏附过程,与炎症或缺血再灌注损伤时白细胞的募集有关。心肌缺血再灌注损伤时E-选择素表达明显增加,降低E选-择素的表达或阻断其作用可减轻缺血再灌注损伤。 |
| 关 键 词： | E-选择素 心肌缺血再灌注损伤 |
| 文章编号： | 1004-3934(2006)05-0637-03 |
| 收稿时间： | 2005-12-12 |
| 修稿时间： | 2006-03-28 |
E-Selectin and Ischemia-Reperfusion Injury in the Heart |
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| DONG Cun-nan,LIU Yue-chun. E-Selectin and Ischemia-Reperfusion Injury in the Heart[J]. Advances in Cardiovascular Diseases, 2006, 27(5): 637-639 | |
| Authors: | DONG Cun-nan LIU Yue-chun |
| Affiliation: | Department of Physiology , Weifang Medical College, Weifang 261042, China |
| Abstract: | E-selectin is a kind of glycoprotein expressed in the vascular endothelial cell.E-selectin may play an important role in the adhesion of leukocytes to the vascular endothelium and is related to the recruitment of leukocytes during ischemia-reperfusion injury in the heart.The expression of E-selectin can be increased significantly during ischemia-reperfusion injury.A protective effect can be obtained by blocking the expression of ligands of E-selectin. |
| Keywords: | E-selectin ischemia-reperfusion injury |
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