43例鼻咽,鼻腔恶性淋巴瘤的临床病理及免疫表型研究

本文对遵义地区４３例鼻咽、鼻腔恶淋巴瘤的临床病理及免疫学表型进行了研究，结果显示：全部病例均为弥漫型，无１例滤泡型，组织学类型以多表细胞性淋巴瘤为主，共３３例（包括小细胞型１３例，中多形１５例，大多形５例），占７６．７％。用ＵＣＨＬ－１、ＣＤ２０和Ｍａｃ３８７等多单克隆抗体进行免疫表型研究。显示Ｔ细胞淋巴瘤３７例（８６％），Ｂ细胞淋巴瘤４例（９．３％），无１例组织细胞性淋巴瘤。鼻咽部Ｔ．Ｂ淋巴瘤比

Clinicopathological and Immunophenotypic Study of 43 Cases of Malignant Nasopharyngeal/ Nasal Lymphoma

The clinicopathological and immunophenotypicfeature of 43 cases malignant nasopharyngeal /nasallymphoma were studied, The results showed thatthey were all of diffues type,no one follicular typewas found. Out of 33 (76. 7% ) Cases including smallcell type 13,medium cell 15,large cell type 5 morpho-logically,pleomophism cell type lymphoma were seenin this series. They were analyzed with monoclonalantibodes UCHL - 1, CD20, and Mac387. Amongthem, there were 37 T -cell lymphoma (86% ) and 4B - cell lymphoma (9. 3%), No histiocytic type wasfound. The ratio of T and B cell lymphoma was dif-ferent in nasopharyngeal lymphoma (T: B=20: 2)and nasal lymphoma (T: B= 16: 2). Clinically,theratio of male to female was 3. 3: 1,the mean age was41 years old, 55. 8% of cases were higher malignantgrade, in addition, dignosis, morbidity and diffrentialdiagnosis were discussed.