曲美他嗪、左卡尼汀及黄芪注射液治疗急性病毒性心肌炎的临床分析

目的探讨曲美他嗪、左卡尼汀及黄芪注射液联合治疗急性病毒性心肌炎（AVM）的临床疗效。方法将符合AVM诊断标准的112例患者随机分为两组（观察组与对照组）,每组56例,对照组给予黄芪注射液联合左卡尼汀治疗,观察组则在对照组的基础上加用曲美他嗪治疗,观察两组患者的心电图、临床症状、血清学指标改善情况及心功能变化。结果观察组总有效率为98.21%,对照组总有效率为82.14%,两组比较差异有统计学意义（P〈0.05）;疗程结束后,观察组患者的临床症状改善率明显高于对照组,且差异有统计学意义（P〈0.05）;观察组患者治疗后的心功能改善情况明显优于对照组,差异有统计学意义（P〈0.05）。结论曲美他嗪、左卡尼汀及黄芪注射液联合治疗AVM,可以提高临床总有效率,改善患者症状、心电图变化与心肌酶谱,恢复心功能,不良反应轻微,可阻止心肌细胞损伤,可作为AVM的治疗方案。

Clinical analysis of trimetazidine, levocarnitine and Huangqi injection in the treatment of acute viral myocarditis

Objective To discuss the clinical effect of the trimetazidine,levocarnitine and Huangqi injection in the treatment of acute viral myocarditis. Methods 112 patients with AVM were randomly divided into two groups（observa- tion group and control group）,56 cases in each group, the control group was treated by the Huangqi injection combined with levocarnitine, and the observation group was treated by the trimetazidine on the basis of the control group, and the electrocardiographic,the improvement of clinical symptoms, the improvement of serum markers situation, cardiac function of two groups were observed. Results The total effective rate of the observation group was 98.21%, the control group was 82.14%, the difference was statistically significant（P〈0.05）. After the treatment, the clinical improvement rate of the observation group was significantly higher than the control group, and the difference was statistically significant （P〈0.05）. The cardiac function improvement rate of the observation group was better than the control group, and the difference was statistically significant（P〈0.05）.Conclusion The trimetazidine,levocarnitine and Huangqi injection in the treatment of the acute viral myocarditis, can improve the total effective rate, improve symptoms, ECG and myocardial enzymes, restore heart function, prevent myocardial injury and adverse reactions are mild, so it canbe used as AVM treatment methods.